YRC Public Data Repository - Protein Structure Prediction

Protein:	EIF1_MOUSE
Organism:	Mus musculus
Length:	113 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EIF1_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|94365786, gi\|... - gi\|94365786\|ref\|XP_997192.1\| PREDICTED: similar to suppressor of initiator codon mutations, related ...	186.0	[0..1]	[112..130]
gi\|114667151 - gi\|114667151\|ref\|XP_511489.2\| PREDICTED: similar to isolog of yeast sui1 and rice gos2; putative [Pa...	184.0	[0..1]	[113..138]
gi\|109115342 - gi\|109115342\|ref\|XP_001092971.1\| PREDICTED: similar to Eukaryotic translation initiation factor 1 (e...	184.0	[0..1]	[113..263]
gi\|113411549, gi... - gi\|113412478\|ref\|XP_001131332.1\| PREDICTED: similar to suppressor of initiator codon mutations, rela...	183.0	[0..3]	[113..179]
gi\|50760847 - gi\|50760847\|ref\|XP_418159.1\| PREDICTED: similar to Eukaryotic translation initiation factor 1 (eIF1)...	181.0	[0..1]	[113..253]
gi\|109474639, gi... - gi\|109476104\|ref\|XP_001070988.1\| PREDICTED: similar to suppressor of initiator codon mutations, rela...	179.0	[0..1]	[113..90]

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Predicted Domain #1

Region A:
Residues: [1-113]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAIQNLHSF DPFADASKGD DLLPAGTEDY IHIRIQQRNG RKTLTTVQGI ADDYDKKKLV  60
   61 KAFKKKFACN GTVIEHPEYG EVIQLQGDQR KNICQFLIEI GLAKDDQLKV HGF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.0
Match:	2if1A
Description:	HUMAN TRANSLATION INITIATION FACTOR EIF1, NMR, 29 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation initiation factor activity	6.56930940751046	bayes_pls_golite062009
nucleic acid binding	2.96971687610169	bayes_pls_golite062009
binding	2.42849959483419	bayes_pls_golite062009
translation regulator activity	2.27579767245564	bayes_pls_golite062009
translation factor activity, nucleic acid binding	2.25914933413253	bayes_pls_golite062009
protein binding	0.420735403363425	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: