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View Structure Prediction Details

Protein: BAMBI_MOUSE
Organism: Mus musculus
Length: 260 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BAMBI_MOUSE.

Description E-value Query
Range
Subject
Range
BAMBI_RAT - BMP and activin membrane-bound inhibitor homolog OS=Rattus norvegicus GN=Bambi PE=2 SV=1
557.0 [0..1] [260..1]
BAMBI - BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
gi|208965888, gi... - gi|61362169|gb|AAX42171.1| BMP and activin membrane-bound inhibitor-like [synthetic construct], gi|6...
556.0 [0..1] [260..1]
gi|60653877, gi|... - gi|60653879|gb|AAX29632.1| BMP and activin membrane-bound inhibitor-like [synthetic construct], gi|6...
556.0 [0..1] [260..1]
gi|109088560 - gi|109088560|ref|XP_001106773.1| PREDICTED: BMP and activin membrane-bound inhibitor homolog (Xenopu...
554.0 [0..1] [260..1]
gi|57039467 - gi|57039467|ref|XP_544209.1| PREDICTED: similar to BMP and activin membrane-bound inhibitor homolog ...
554.0 [0..1] [260..1]
BAMBI_SHEEP - BMP and activin membrane-bound inhibitor homolog OS=Ovis aries GN=BAMBI PE=2 SV=1
551.0 [0..1] [260..1]
gi|76632321, gi|... - gi|92096613|gb|AAI14656.1| BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) [Bos ta...
550.0 [0..1] [260..1]
gi|14328907 - gi|14328907|gb|AAK60413.1|AF153440_1 Nma [Mus musculus]
544.0 [0..1] [260..1]
gi|6006630 - gi|6006630|emb|CAB56858.1| BAMBI protein [Xenopus laevis]
527.0 [0..1] [260..1]

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Predicted Domain #1
Region A:
Residues: [1-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRHSSYFFI WLQLELCAMA VLLTKGEIRC YCDAAHCVAT GYMCKSELSA CFSRLLDPQN  60
   61 TNSPLTHGCL DSLASTADIC RAKQAQNHSG PAMPTLECCH EDMCNYRGLH DVLSPSKSEA 120
  121 SGQGNRYQHD SSRNLITKMQ ELTSSKELWF RAAVIAVPIA GGLILVLLIM LALRMLRS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.1
Match: 1rewC
Description: Structural refinement of the complex of bone morphogenetic protein 2 and its type IA receptor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor activity 2.64910374554654 bayes_pls_golite062009
signal transducer activity 2.43282761870804 bayes_pls_golite062009
molecular transducer activity 2.43282761870804 bayes_pls_golite062009
binding 1.74649131569568 bayes_pls_golite062009
transforming growth factor beta binding 1.53779699320828 bayes_pls_golite062009
SMAD binding 1.15687191322558 bayes_pls_golite062009
protein binding 1.15266632427905 bayes_pls_golite062009
receptor binding 1.07792597575757 bayes_pls_golite062009
growth factor binding 0.896615500077067 bayes_pls_golite062009
receptor serine/threonine kinase binding 0.679269866160119 bayes_pls_golite062009
transforming growth factor beta receptor binding 0.614566148594713 bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase binding 0.614566148594713 bayes_pls_golite062009
type I transforming growth factor beta receptor binding 0.486943436794948 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [179-260]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENKRLQDERQ QMLSRLHYSF HGHHSKKGQV AKLDLECMVP VSGQENCCLT CDKMRQAELS  60
   61 NEKILSLVHW GMYSGHGKLE FI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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