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View Structure Prediction Details

Protein: SCN1B_MOUSE
Organism: Mus musculus
Length: 218 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SCN1B_MOUSE.

Description E-value Query
Range
Subject
Range
gi|1513184 - gi|1513184|gb|AAB06745.1| immunoglobulin kappa chain
191.0 [0..1] [210..1]
gi|21706664 - gi|21706664|gb|AAH34142.1| IGKV1-5 protein [Homo sapiens]
184.0 [0..4] [210..7]
gi|243868 - gi|243868|gb|AAB21182.1| immunoglobulin light chain [Rattus sp.]
182.0 [0..1] [210..1]

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Predicted Domain #1
Region A:
Residues: [1-218]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTLLALVVG AALVSSAWGG CVEVDSDTEA VYGMTFKILC ISCKRRSETT AETFTEWTFR  60
   61 QKGTEEFVKI LRYENEVLQL EEDERFEGRV VWNGSRGTKD LQDLSIFITN VTYNHSGDYE 120
  121 CHVYRLLFFD NYEHNTSVVK KIHLEVVDKA NRDMASIVSE IMMYVLIVVL TIWLVAEMVY 180
  181 CYKKIAAATE AAAQENASEY LAITSESKEN CTGVQVAE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.09691
Match: 1iqwL
Description: Immunoglobulin light chain kappa variable domain, VL-kappa; Immunoglobulin light chain kappa constant domain, CL-kappa
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor activity 3.0754311615326 bayes_pls_golite062009
signal transducer activity 2.92683710723714 bayes_pls_golite062009
molecular transducer activity 2.92683710723714 bayes_pls_golite062009
transmembrane receptor activity 2.79758224858792 bayes_pls_golite062009
binding 2.31245946376548 bayes_pls_golite062009
protein binding 1.15877334904406 bayes_pls_golite062009
peptide antigen binding 0.87387132710884 bayes_pls_golite062009
olfactory receptor activity 0.76374091031142 bayes_pls_golite062009
cell adhesion molecule binding 0.63737386998612 bayes_pls_golite062009
integrin binding 0.599569390248921 bayes_pls_golite062009
receptor binding 0.125304929251743 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle