YRC Public Data Repository - Protein Structure Prediction

Protein:	TCF21_MOUSE
Organism:	Mus musculus
Length:	179 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TCF21_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|34853278, gi\|... - gi\|74048316\|ref\|NP_001027569.1\| transcription factor 21 [Rattus norvegicus], gi\|71680095\|gb\|AAI00107...	117.0	[0..1]	[179..1]
gi\|2801465, gi\|9... - gi\|9629901\|ref\|NP_045935.1\| p110 [Avian myelocytomatosis virus], gi\|61609\|emb\|CAA24499.1\| p96 polypr... gi\|625263 - gi\|625263\|pir\|\|FOFV29 gag-myc polyprotein - avian myelocytomatosis virus MC29 (provirus)	117.0	[0..10]	[162..726]
gi\|16611800 - gi\|16611800\|gb\|AAL27367.1\| myogenic factor 5 [Equus caballus]	116.0	[0..7]	[178..10]
TCF21_BOVIN - Transcription factor 21 OS=Bos taurus GN=TCF21 PE=2 SV=1	114.0	[0..1]	[179..1]
gi\|60810272 - gi\|60810272\|gb\|AAX36143.1\| transcription factor 21 [synthetic construct]	114.0	[0..1]	[179..1]
gi\|208968819, gi... - gi\|61355948\|gb\|AAX41193.1\| transcription factor 21 [synthetic construct], gi\|208968819\|dbj\|BAG74248.... TCF21 - transcription factor 21 gi\|114609377 - gi\|114609377\|ref\|XP_518871.2\| PREDICTED: transcription factor 21 isoform 2 [Pan troglodytes]	113.0	[0..1]	[179..1]
gi\|50742734 - gi\|50742734\|ref\|XP_419734.1\| PREDICTED: similar to TCF21 [Gallus gallus]	113.0	[0..1]	[179..1]
TCF21_XENLA - Transcription factor 21 OS=Xenopus laevis GN=tcf21 PE=2 SV=1	113.0	[0..1]	[179..1]

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Predicted Domain #1

Region A:
Residues: [1-179]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTGSLSDVE DLQEVEMLDC DSLKVDSNKE FGTSNESTEE GSNCENGSPQ KGRGGLGKRR  60
   61 KAPTKKSPLS GVSQEGKQVQ RNAANARERA RMRVLSKAFS RLKTTLPWVP PDTKLSKLDT 120
  121 LRLASSYIAH LRQILANDKY ENGYIHPVNL TWPFMVAGKP ENDLKEVVTA NRLCGTTAS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	16.221849
Match:	1nkpA
Description:	Myc prot-oncogene protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.04189889011459	bayes_pls_golite062009
DNA binding	1.57198412842008	bayes_pls_golite062009
transcription regulator activity	1.51367486803231	bayes_pls_golite062009
transcription factor activity	1.48896865387791	bayes_pls_golite062009
protein binding	0.90375176425983	bayes_pls_golite062009
nucleic acid binding	0.863712081656127	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: