YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|219518472, gi...
Organism:	Mus musculus
Length:	169 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|219518472, gi....

Description	E-value	Query Range	Subject Range
gi\|109502386, gi... - gi\|62661923\|ref\|XP_577423.1\| PREDICTED: similar to interleukin 17E [Rattus norvegicus], gi\|109502386...	213.0	[0..1]	[169..1]
gi\|18034676 - gi\|18034676\|gb\|AAL57622.1\|AF458059_1 IL25 [Homo sapiens]	195.0	[0..1]	[169..1]
gi\|55640557 - gi\|55640557\|ref\|XP_522801.1\| PREDICTED: interleukin 25 isoform 2 [Pan troglodytes]	193.0	[0..1]	[169..1]
gi\|17266280 - gi\|17266280\|gb\|AAK59816.1\| interleukin 17E precursor [Mus musculus]	192.0	[0..17]	[169..1]
gi\|73962631 - gi\|73962631\|ref\|XP_537375.2\| PREDICTED: similar to interleukin 17E [Canis familiaris]	188.0	[0..1]	[169..1]
gi\|76626950 - gi\|76626950\|ref\|XP_605190.2\| PREDICTED: similar to interleukin 25 [Bos taurus]	185.0	[0..3]	[169..28]
gi\|109082965 - gi\|109082965\|ref\|XP_001107963.1\| PREDICTED: similar to interleukin 25 isoform 2 isoform 2 [Macaca mu...	183.0	[0..1]	[169..1]

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Predicted Domain #1

Region A:
Residues: [1-169]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYQAVAFLAM IVGTHTVSLR IQEGCSHLPS CCPSKEQEPP EEWLKWSSAS VSPPEPLSHT  60
   61 HHAESCRASK DGPLNSRAIS PWSYELDRDL NRVPQDLYHA RCLCPHCVSL QTGSHMDPLG 120
  121 NSVPLYHNQT VFYRRPCHGE EGTHRRYCLE RRLYRVSLAC VCVRPRVMA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.0
Match:	1jpyA
Description:	Interleukin 17F, IL-17F
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
receptor binding	2.57179338290723	bayes_pls_golite062009
protein binding	2.39087599465488	bayes_pls_golite062009
binding	2.20424876168895	bayes_pls_golite062009
protein dimerization activity	0.780490196640171	bayes_pls_golite062009
protein homodimerization activity	0.566286496680472	bayes_pls_golite062009
cell surface binding	0.560163140281564	bayes_pls_golite062009
growth factor activity	0.493716788735435	bayes_pls_golite062009
identical protein binding	0.407140308548171	bayes_pls_golite062009
cytokine activity	0.376603864339999	bayes_pls_golite062009
receptor serine/threonine kinase binding	0.238465525843413	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: