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View Structure Prediction Details

Protein: PUF6_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 642 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PUF6_SCHPO.

Description E-value Query
Range
Subject
Range
gi|109479064 - gi|109479064|ref|XP_001068003.1| PREDICTED: similar to Pumilio homolog 2 [Rattus norvegicus]
398.0 [0..20] [489..583]
gi|73979795 - gi|73979795|ref|XP_849088.1| PREDICTED: similar to pumilio homolog 2 isoform 1 [Canis familiaris]
397.0 [0..20] [489..595]
gi|114576341, gi... - gi|114576341|ref|XP_001140758.1| PREDICTED: pumilio homolog 2 isoform 11 [Pan troglodytes], gi|11457...
397.0 [0..20] [489..597]
gi|168267226 - gi|168267226|dbj|BAG09669.1| pumilio homolog 2 [synthetic construct]
gi|85567007, gi|... - gi|85567007|gb|AAI12049.1| Pumilio homolog 2 [Homo sapiens], gi|85566710|gb|AAI12047.1| Pumilio homo...
397.0 [0..20] [489..596]
gi|109102137, gi... - gi|109102137|ref|XP_001095963.1| PREDICTED: similar to pumilio homolog 2 isoform 4 [Macaca mulatta],...
396.0 [0..20] [489..597]
gi|82569974, gi|... - gi|86129498|ref|NP_001034381.1| pumilio homolog 2 [Gallus gallus], gi|82569974|gb|ABB83589.1| pumili...
396.0 [0..20] [489..593]

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Predicted Domain #1
Region A:
Residues: [1-111]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIGKRKEST EVKKKDGSMN KRVKVAKLPK KVDSFSPKKK KNTTSSGSSE SDSMSQNDKK  60
   61 KDSSLNESED EDFAGFGESA SENDELESAE SEAENDEESS SQKSNSKESH A

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [112-486]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRKKLQKERK AMKPFADTSL KAKSLWDKLR QKTSIKAEER KTIIAELFDL IRTNVKQLVF  60
   61 KHDMSRVVQT CVKFGSKQQR ETICAELAGS YVDLCKSPYG KYLAIKIFKY GTPKMKEVIL 120
  121 GEMYGNVVKM IRHREAAYVV EDAFREFTNL QQQRALICEF YGPEFQVFKD RTQDIHIDKL 180
  181 LIDHPEKRPS IMQNLWKTIE GSIAKGSIGF TMVHRAMLEF INHADSNEAK ELLNLTKELI 240
  241 YEFVHTRDGS QVAMKLFALA NAKDRKVMLK SLRPYLIETA KDSYGHLVVV AALDCTDDTI 300
  301 MTGKLLQAEF EGELLKLSAD KFARRILLYV LVGWEDARYF SKENRELLRS LDSLKAKTSK 360
  361 KDPIVRRNEL KATIG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.09691
Match: 1ib2A
Description: Pumilio 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.43298635785702 bayes_pls_golite062009
protein binding 1.50566694420704 bayes_pls_golite062009
RNA binding 1.20550543134698 bayes_pls_golite062009
structural molecule activity 1.20255343083458 bayes_pls_golite062009
nucleic acid binding 0.169755106399802 bayes_pls_golite062009
cytoskeletal protein binding 0.0330689772947346 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [487-642]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLLISLISKA AGDMIAESLA SQVLVDALLY APCEKEEAVD ATLKAFDGNP EQDNHLIHQI  60
   61 HCSRALKTLV QNGHWSGAEK QVVKAEDDLK VASKLIVIIK KYLVEWASGD GAFVVVAVLE 120
  121 ALSDSEKQEF LKILRKHKNQ LNKSEFRGTK KLLEML

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.04
Match: 1ib2A
Description: Pumilio 1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle