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View Structure Prediction Details

Protein: PVH1_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 330 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PVH1_SCHPO.

Description E-value Query
Range
Subject
Range
DUS12_RAT - Dual specificity protein phosphatase 12 OS=Rattus norvegicus GN=Dusp12 PE=2 SV=1
279.0 [0..26] [329..6]
DUS12_MOUSE - Dual specificity protein phosphatase 12 OS=Mus musculus GN=Dusp12 PE=2 SV=1
276.0 [0..27] [329..7]
DUSP12 - dual specificity phosphatase 12
gi|60656185, gi|... - gi|60656185|gb|AAX32656.1| dual specificity phosphatase 12 [synthetic construct], gi|123998709|gb|AB...
ENSPTRT00000002905 - null
273.0 [0..20] [329..1]
gi|109017861 - gi|109017861|ref|XP_001118147.1| PREDICTED: similar to dual specificity phosphatase 12 [Macaca mulat...
271.0 [0..20] [329..1]
gi|57111449 - gi|57111449|ref|XP_536142.1| PREDICTED: similar to dual specificity phosphatase 12 [Canis familiaris...
270.0 [0..29] [329..8]
gi|55593863 - gi|55593863|ref|XP_514446.1| PREDICTED: dual specificity phosphatase 12 [Pan troglodytes]
268.0 [0..19] [329..13]
gi|74268175 - gi|74268175|gb|AAI03263.1| DUSP12 protein [Bos taurus]
264.0 [0..28] [329..2]
PVH1_YEAST - Tyrosine-protein phosphatase YVH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YVH1 P...
YVH1 - Protein phosphatase involved in vegetative growth at low temperatures, sporulation, and glycogen acc...
248.0 [0..46] [325..11]
gi|62857951, gi|... - gi|89272101|emb|CAJ81754.1| dual specificity phosphatase 12 [Xenopus tropicalis], gi|62857951|ref|NP...
247.0 [0..47] [329..1]

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Predicted Domain #1
Region A:
Residues: [1-206]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNKSAWQPQ FDEIHSSVQE AEGFLQSSND VQKAIDEVHY PDSLNDLSEI SKNLYISSWK  60
   61 TASELVSTSD KGIDYTLSAM SINPNLSVPE QQHLWLQIED SSSQNILQYF EKSNKFIAFA 120
  121 LSKNAKVLVH CFAGISRSVT LVAAYLMKEN NWNTEEALSH INERRSGISP NANFLRQLRV 180
  181 YFECNYQLDR SLRPYRQWLF RRYGDF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.522879
Match: 1wrmA
Description: Crystal structure of JSP-1
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [207-330]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVLNTRVPSE VAYAETVRAR AGQLELRCKK CRFVLASSDY LVSHEPKDEN NYSHTRCTHY  60
   61 FLEPIRWMQP ELELGNLEGR FDCPKCNSKI GSYKWQGLQC SCLQWVCPAL SILQSRVDAV 120
  121 RKLG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.968
Match: 2dlqA
Description: No description for 2dlqA was found.

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.68743405828801 bayes_pls_golite062009
nucleic acid binding 3.68045904515072 bayes_pls_golite062009
DNA binding 3.67134559212672 bayes_pls_golite062009
binding 2.99742524370422 bayes_pls_golite062009
transcription factor activity 2.74156749164617 bayes_pls_golite062009
protein binding 2.00293511941456 bayes_pls_golite062009
transcription activator activity 1.65132234119107 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.59379135382987 bayes_pls_golite062009
transcription repressor activity 1.16015561891665 bayes_pls_golite062009
sequence-specific DNA binding 1.02112591326973 bayes_pls_golite062009
transcription factor binding 0.992551517825148 bayes_pls_golite062009
chromatin binding 0.882614685845383 bayes_pls_golite062009
structure-specific DNA binding 0.77786753211873 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.429714523640337 bayes_pls_golite062009
double-stranded DNA binding 0.356308409912021 bayes_pls_golite062009
transcription cofactor activity 0.336256827445227 bayes_pls_golite062009
catalytic activity 0.263007611601737 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle