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View Structure Prediction Details

Protein: HA2B_MOUSE
Organism: Mus musculus
Length: 256 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HA2B_MOUSE.

Description E-value Query
Range
Subject
Range
gi|8117746 - gi|8117746|gb|AAF72752.1|AF165353_1 MHC class I antigen [Pan troglodytes]
312.0 [0..2] [254..91]
gi|37958135 - gi|37958135|gb|AAP40298.1| MHC class I antigen [Saimiri sciureus sciureus]
309.0 [0..3] [253..92]
gi|506662 - gi|506662|gb|AAA88850.1| MHC class I A
309.0 [0..3] [254..84]

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Predicted Domain #1
Region A:
Residues: [1-256]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRSRALILG VLALTTMLSL CGGEDDIEAD HVGTYGISVY QSPGDIGQYT FEFDGDELFY  60
   61 VDLDKKETVW MLPEFGQLAS FDPQGGLQNI AVVKHNLGVL TKRSNSTPAT NEAPQATVFP 120
  121 KSPVLLGQPN TLICFVDNIF PPVINITWLR NSKSVADGVY ETSFFVNRDY SFHKLSYLTF 180
  181 IPSDDDIYDC KVEHWGLEEP VLKHWEPEIP APMSELTETV VCALGLSVGL VGIVVGTIFI 240
  241 IQGLRSGGTS RHPGPL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.221849
Match: 1iakA
Description: Class II MHC alpha chain, C-terminal domain; Class II MHC alpha chain, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptide antigen binding 11.0753660234769 bayes_pls_golite062009
olfactory receptor activity 8.50611980376815 bayes_pls_golite062009
antigen binding 7.67141746788228 bayes_pls_golite062009
endogenous lipid antigen binding 3.6120042602684 bayes_pls_golite062009
MHC class I receptor activity 3.46497995701625 bayes_pls_golite062009
receptor activity 3.04238248088254 bayes_pls_golite062009
transmembrane receptor activity 2.91649681515985 bayes_pls_golite062009
natural killer cell lectin-like receptor binding 2.87337850935774 bayes_pls_golite062009
signal transducer activity 2.59970257426838 bayes_pls_golite062009
molecular transducer activity 2.59970257426838 bayes_pls_golite062009
IgG binding 2.59905791929203 bayes_pls_golite062009
protein binding 2.20481087437436 bayes_pls_golite062009
binding 2.11682283742138 bayes_pls_golite062009
lipid antigen binding 2.09050740693882 bayes_pls_golite062009
fibroblast growth factor 1 binding 1.37360564853216 bayes_pls_golite062009
growth factor binding 1.1520564031101 bayes_pls_golite062009
IgG receptor activity 1.15013317153047 bayes_pls_golite062009
receptor binding 0.96769592478452 bayes_pls_golite062009
fibroblast growth factor binding 0.962566971314929 bayes_pls_golite062009
exogenous lipid antigen binding 0.763929387638141 bayes_pls_golite062009
coreceptor activity 0.661209696849389 bayes_pls_golite062009
IgE receptor activity 0.54373753879821 bayes_pls_golite062009
IgE binding 0.54373753879821 bayes_pls_golite062009
G-protein coupled receptor activity 0.4860421936 bayes_pls_golite062009
MHC class II receptor activity 0.251167772391909 bayes_pls_golite062009
peptide binding 0.2334349814724 bayes_pls_golite062009

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