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View Structure Prediction Details

Protein: PPX1_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 384 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PPX1_SCHPO.

Description E-value Query
Range
Subject
Range
gi|73981563 - gi|73981563|ref|XP_540307.2| PREDICTED: similar to prune homolog [Canis familiaris]
291.0 [0..22] [379..104]
gi|109016104 - gi|109016104|ref|XP_001103486.1| PREDICTED: similar to prune homolog [Macaca mulatta]
286.0 [0..22] [379..10]
gi|123985899, gi... - gi|123998950|gb|ABM87064.1| prune homolog (Drosophila) [synthetic construct], gi|123985899|gb|ABM837...
PRUNE - prune homolog (Drosophila)
285.0 [0..22] [379..10]
PRUNE_MOUSE - Protein prune homolog OS=Mus musculus GN=Prune PE=1 SV=1
275.0 [0..22] [379..10]
PRUNE_BOVIN - Protein prune homolog OS=Bos taurus GN=PRUNE PE=2 SV=1
273.0 [0..22] [379..10]
PRUNE_RAT - Protein prune homolog OS=Rattus norvegicus GN=Prune PE=1 SV=1
270.0 [0..22] [379..10]
gi|46121271, gi|... - gi|46121271|ref|XP_385190.1| hypothetical protein FG05014.1 [Gibberella zeae PH-1], gi|42551136|gb|E...
260.0 [0..1] [380..5]

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Predicted Domain #1
Region A:
Residues: [1-384]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLGRFLENG REQIRNLLLN ASTVSSAPSF SFVSGNESAD LDSCASSIVY AYCLQRKQLG  60
   61 RIVVPFFNIP RKELRLRPEL SYLLNLASIS SDDIVFLDDI VKLPKRIFSN PIYLVDHNSL 120
  121 DRKDLENFNG SIAGIIDHHK DEGGSLHADP RIIEECGSCC TLVCRYFMPV IRSLYDSKVS 180
  181 ELHQTATNLA VLALGPILID TGNLKNEKTT DTDVKIVNDL CSFVPKDWVR DEFFDTLKEK 240
  241 KKSCKGFSFD DLLRRDLKQY FPDGIVVNYA SVGKGLDWIK KKRLGWEDEL KSFAEVQNSD 300
  301 LVIVGLSLSK NDEFGRQLIL YKRTERGAGL ADSFLKLSKQ NLGLEIIEEK DNGDLSMWNQ 360
  361 RNSAASRKKV VPLLMDSVKQ VASK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.221849
Match: 1wppA
Description: Structure of Streptococcus gordonii inorganic pyrophosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nuclease activity 2.22762374984422 bayes_pls_golite062009
hydrolase activity 2.11996205929773 bayes_pls_golite062009
catalytic activity 1.78154379547895 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.7679956422453 bayes_pls_golite062009
deoxyribonuclease activity 1.7238398802096 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.48438369225803 bayes_pls_golite062009
exonuclease activity 1.4791620684568 bayes_pls_golite062009
binding 1.44809983424821 bayes_pls_golite062009
single-stranded DNA specific exodeoxyribonuclease activity 1.10404503151762 bayes_pls_golite062009
exodeoxyribonuclease activity 0.808006273031307 bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.792120683260194 bayes_pls_golite062009
protein binding 0.409982335293186 bayes_pls_golite062009
inorganic diphosphatase activity 0.158887418739632 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle