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View Structure Prediction Details

Protein: PAC1_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 363 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PAC1_SCHPO.

Description E-value Query
Range
Subject
Range
gi|109466164 - gi|109466164|ref|XP_001058381.1| PREDICTED: similar to ribonuclease III [Rattus norvegicus]
280.0 [0..1] [353..949]
gi|73953918 - gi|73953918|ref|XP_868248.1| PREDICTED: similar to Ribonuclease III (RNase III) (Drosha) (p241) isof...
278.0 [0..1] [353..591]
gi|114600825 - gi|114600825|ref|XP_001157646.1| PREDICTED: ribonuclease III, nuclear isoform 8 [Pan troglodytes]
278.0 [0..1] [353..918]
RNASEN - ribonuclease type III, nuclear
277.0 [0..1] [353..949]
gi|34784428 - gi|34784428|gb|AAH57687.1| Rnasen protein [Mus musculus]
277.0 [0..1] [353..517]

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Predicted Domain #1
Region A:
Residues: [1-104]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRFKRHHEG DSDSSSSASD SLSRGRRSLG HKRSSHIKNR QYYILEKKIR KLMFAMKALL  60
   61 EETKHSTKDD VNLVIPGSTW SHIEGVYEML KSRHDRQNEP VIEE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [105-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSSHPKNQKN QENNEPTSEE FEEGEYPPPL PPLRSEKLKE QVFMHISRAY EIYPNQSNPN  60
   61 ELLDIHNERL EFLGDSFFNL FTTRIIFSKF PQMDEGSLSK LRAKFVGNES ADKFARLYGF 120
  121 DKTLVLSYSA EKDQLRKSQK VIADTFEAYL GALILDGQEE TAFQWVSRLL QPKIANITVQ 180
  181 RPIDKLAKSK LFHKYSTLGH IEYRWVDGAG GSAEGYVIAC IFNGKEVARA WGANQKDAGS 240
  241 RAAMQALEVL AKDYSKFAR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.69897
Match: 1o0wA
Description: RNase III endonuclease catalytic domain; RNase III, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 3.49736268261512 bayes_pls_golite062009
binding 3.09705138687537 bayes_pls_golite062009
nucleic acid binding 2.95361490759242 bayes_pls_golite062009
endoribonuclease activity 1.62086478301433 bayes_pls_golite062009
DNA binding 1.51133867432475 bayes_pls_golite062009
double-stranded RNA binding 1.46317494664076 bayes_pls_golite062009
protein binding 1.33336414936007 bayes_pls_golite062009
structural constituent of ribosome 1.33042413200827 bayes_pls_golite062009
transcription regulator activity 1.25950932467779 bayes_pls_golite062009
structural molecule activity 1.17628321323282 bayes_pls_golite062009
transcription factor activity 0.42419387757895 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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