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View Structure Prediction Details

Protein: SCD1_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 872 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SCD1_SCHPO.

Description E-value Query
Range
Subject
Range
gi|67538844, gi|... - gi|67538844|ref|XP_663196.1| hypothetical protein AN5592.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
385.0 [0..45] [868..12]
gi|32410883, gi|... - gi|32410883|ref|XP_325922.1| hypothetical protein [Neurospora crassa], gi|28921285|gb|EAA30594.1| hy...
gi|85094135 - gi|85094135|ref|XP_959830.1| hypothetical protein [Neurospora crassa OR74A]
369.0 [0..9] [868..6]
gi|83768037 - gi|83768037|dbj|BAE58176.1| unnamed protein product [Aspergillus oryzae]
gi|169771417 - gi|169771417|ref|XP_001820178.1| hypothetical protein [Aspergillus oryzae RIB40]
gi|220699132, gi... - gi|238486030|ref|XP_002374253.1| Rho guanyl nucleotide exchange factor, putative [Aspergillus flavus...
368.0 [0..51] [868..17]
gi|115391219, gi... - gi|115391219|ref|XP_001213114.1| conserved hypothetical protein [Aspergillus terreus NIH2624], gi|11...
365.0 [0..51] [870..17]
gi|70993676, gi|... - gi|70993676|ref|XP_751685.1| Rho guanyl nucleotide exchange factor [Aspergillus fumigatus Af293], gi...
358.0 [0..45] [870..11]
gi|42546940, gi|... - gi|46137993|ref|XP_390687.1| hypothetical protein FG10511.1 [Gibberella zeae PH-1], gi|42546940|gb|E...
355.0 [0..9] [787..4]
gi|109109865 - gi|109109865|ref|XP_001099413.1| PREDICTED: vav 2 oncogene isoform 3 [Macaca mulatta]
352.0 [0..77] [737..1]
gi|109469461 - gi|109469461|ref|XP_001075315.1| PREDICTED: similar to Protein vav-2 isoform 1 [Rattus norvegicus]
352.0 [0..77] [737..1]
VAV2_MOUSE - Guanine nucleotide exchange factor VAV2 OS=Mus musculus GN=Vav2 PE=1 SV=1
351.0 [0..77] [737..1]
gi|55960165, gi|... - gi|55960967|emb|CAI12278.1| vav 2 guanine nucleotide exchange factor [Homo sapiens], gi|55960165|emb...
351.0 [0..77] [737..1]

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Predicted Domain #1
Region A:
Residues: [1-127]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYFQDRKTS SRSLPSYINH STQNLVGPRK DETNLSEYMK LRLLQSPSQV IYNLENTVSL  60
   61 YRRCLNLRKR LMDISELAAF FDSIHREALN SSFKILEFKD IEFDDPVTEI WLFCRLGYPL 120
  121 CALFNCL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.30103
Match: 2d86A
Description: No description for 2d86A was found.

Predicted Domain #2
Region A:
Residues: [128-594]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVKQKLEVNS SVSLENTNVC KASLYRFMLM CKNELGLTDA ALFSISEIYK PSTAPLVRAL  60
   61 QTIELLLKKY EVSNTTKSSS TPSPSTDDNV PTGTLNSLIA SGRRVTAELY ETELKYIQDL 120
  121 EYLSNYMVIL QQKQILSQDT ILSIFTNLNE ILDFQRRFLV GLEMNLSLPV EEQRLGALFI 180
  181 ALEEGFSVYQ VFCTNFPNAQ QLIIDNQNQL LKVANLLEPS YELPALLIKP IQRICKYPLL 240
  241 LNQLLKGTPS GYQYEEELKQ GMACVVRVAN QVNETRRIHE NRNAIIELEQ RVIDWKGYSL 300
  301 QYFGQLLVWD VVNVCKADIE REYHVYLFEK ILLCCKEMST LKRQARSISM NKKTKRLDSL 360
  361 QLKGRILTSN ITTVVPNHHM GSYAIQIFWR GDPQHESFIL KLRNEESHKL WMSVLNRLLW 420
  421 KNEHGSPKDI RSAASTPANP VYNRSSSQTS KGYNSSDYDL LRTHSLD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.39794
Match: 2pz1A
Description: No description for 2pz1A was found.

Predicted Domain #3
Region A:
Residues: [595-767]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENVNSPTSIS SPSSKSSPFT KTTSKDTKSA TTTDERPSDF IRLNSEESVG TSSLRTSQTT  60
   61 STIVSNDSSS TASIPSQISR ISQVNSLLND YNYNRQSHIT RVYSGTDDGS SVSIFEDTSS 120
  121 STKQKIFDQP TTNDCDVMRP RQYSYSAGMK SDGSLLPSTK HTSLSSSSTS TSL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [768-872]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVRNTTNVKI RLRLHEVSLV LVVAHDITFD ELLAKVEHKI KLCGILKQAV PFRVRLKYVD  60
   61 EDGDFITITS DEDVLMAFET CTFELMDPVH NKGMDTVSLH VVVYF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.58
Match: 1q1oA
Description: Solution Structure of the PB1 Domain of Cdc24p (Long Form)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.21864685713998 bayes_pls_golite062009
Rho guanyl-nucleotide exchange factor activity 1.03402678056727 bayes_pls_golite062009
protein binding 0.989073783870014 bayes_pls_golite062009
signal transducer activity 0.635646176656368 bayes_pls_golite062009
molecular transducer activity 0.635646176656368 bayes_pls_golite062009
GTPase regulator activity 0.416736165411261 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.416404907234896 bayes_pls_golite062009
phospholipase binding 0.386109322229891 bayes_pls_golite062009
small GTPase regulator activity 0.328454638295227 bayes_pls_golite062009
enzyme regulator activity 0.199913902916545 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.122901168586355 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle