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View Structure Prediction Details

Protein: Dscam-PAD
Organism: Drosophila melanogaster
Length: 2017 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PAD.

Description E-value Query
Range
Subject
Range
Dscam-PAM - The gene Down syndrome cell adhesion molecule is referred to in FlyBase by the symbol Dmel\Dscam (CG...
1498.0 [0..3] [2017..3]

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Predicted Domain #1
Region A:
Residues: [1-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE  60
   61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120
  121 NQFGSIISRD VHVRAVVNQF YGADILMEYV I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 78.09691
Match: 2v5sA
Description: No description for 2v5sA was found.

Predicted Domain #2
Region A:
Residues: [152-817]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGNAAVLKCS IPSFVADFVR VESWIDEEGT ELRPSENYDG KYLVLPSGEL HIREVGPEDG  60
   61 YKSYQCRTKH RLTGETRLSA TKGRLVITEP VGSVAPKISV ENRLKNAEAR IGSTFTLFCP 120
  121 GQAYPVPFFR WYKFIEGTTR KQAVVLNDRV KQVSGTLIIK DAVVEDSGKY LCVVNNSVGG 180
  181 ESVETVLTVT APLSAKIDPP TQTVDFGRPA VFTCQYTGNP IKTVSWMKDG KAIGHSEPVL 240
  241 RIESVKKEDK GMYQCFVRND QESAEASAEL KLGGRFDPPV IRQAFQEETM EPGPSVFLKC 300
  301 VAGGNPTPEI SWELDGKKIA NNDRYQVGQY VTVNGDVVSY LNITSVHAND GGLYKCIAKS 360
  361 KVGVAEHSAK LNVYGLPYIR QMEKKAIVAG ETLIVTCPVA GYPIDSIVWE RDNRALPINR 420
  421 KQKVFPNGTL IIENVERNSD QATYTCVAKN QEGYSARGSL EVQVMVAPKI APFDFGDEPS 480
  481 NFGESASVQC LVTSGDFPVS FAWLFNGREI NENVYDVSMV KLGKKISALS IDIVRDHHAG 540
  541 NYTCVAVNRA TSVNFTAELV VNVPPRWILE PTDKAFAQGS DAKVECKADG FPKPQVTWKK 600
  601 AVGDTPGEYK DLKKSDNIRV EEGTLHVDNI QKTNEGYYLC EAINGIGSGL SAVIMISVQA 660
  661 PPEFTE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.69897
Match: 1e07A
Description: Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [818-896]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLRNQTARRG EPAVLQCEAK GEKPIGILWN MNNMRLDPKN DNRYTIREEI LSTGVMSSLS  60
   61 IKRTERSDSA LFTCVATNA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.154902
Match: 2nziA
Description: No description for 2nziA was found.

Predicted Domain #4
Region A:
Residues: [897-1005]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FGSDDASINM IVQEVPEMPY ALKVLDKSGR SVQLSWAQPY DGNSPLDRYI IEFKRSRASW  60
   61 SEIDRVIVPG HTTEAQVQKL SPATTYNIRI VAENAIGTSQ SSEAVTIIT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.39794
Match: 1ueyA
Description: Solution Structure of The First Fibronectin Type III Domain of Human KIAA0343 protein
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [1006-1115]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEEAPSGKPQ NIKVEPVNQT TMRVTWKPPP RTEWNGEILG YYVGYKLSNT NSSYVFETIN  60
   61 FITEEGKEHN LELQNLRVYT QYSVVIQAFN KIGAGPLSEE EKQFTAEGTP 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.69897
Match: 2edxA
Description: No description for 2edxA was found.

Predicted Domain #6
Region A:
Residues: [1116-1214]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQPPSDTACT TLTSQTIRVG WVSPPLESAN GVIKTYKVVY APSDEWYDET KRHYKKTASS  60
   61 DTVLHGLKKY TNYTMQVLAT TAGGDGVRSV PIHCQTEPD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.39794
Match: 1x5hA
Description: The solution structure of the third fibronectin type III domain of human Neogenin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
pattern binding 0.82756944920828 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [1215-1311]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPEAPTDVKA LVMGNAAILV SWRPPAQPNG IITQYTVYSK AEGAETETKT QKVPHYQMSF  60
   61 EATELEKNKP YEFWVTASTT IGEGQQSKSI VAMPSDQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.39794
Match: 1wfnA
Description: The fourth FN3 domain of human sidekick-2
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [1312-1664]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPAKIASFDD TFTATFKEDA KMPCLAVGAP QPEITWKIKG VEFSANDRMR VLPDGSLLIK  60
   61 SVNRQDAGDY SCHAENSIAK DSITHKLIVL APPQSPHVTL SATTTDALTV KLKPHEGDTA 120
  121 PLHGYTLHYK PEFGEWETSE VSVDSQKHNI EGLLCGSRYQ VYATGFNNIG AGEASDILNT 180
  181 RTKGQKPKLP EKPRFIEVSS NSVSLHFKAW KDGGCPMSHF VVESKKRDQI EWNQISNNVK 240
  241 PDNNYVVLDL EPATWYNLRI TAHNSAGFTV AEYDFATLTV TGGTIAPSRD LPELSAEDTI 300
  301 RIILSNLNLV VPVVAALLVI IIAIIVICIL RSKGNHHKDD VVYNQTMGPG ATL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.69897
Match: 2v5yA
Description: No description for 2v5yA was found.

Predicted Domain #9
Region A:
Residues: [1665-1831]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKRRPDLRDE LGYIAPPNRK LPPVPGSNYN TCDRIKRGRG GLRSNHSTWD PRRNPNLYEE  60
   61 LKAPPVPMHG NHYGHAHGNA ECHYRHPGME DEICPYATFH LLGFREEMDP TKAMNFQTFP 120
  121 HQNGHAGPVP GHAGTMLPPG HPGHVHSRSG SQSMPRANRY QRKNSQG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1832-1938]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQSSIYTPAP EYDDPANCAE EDQYRRYTRV NSQGGSLYSG PGPEYDDPAN CAPEEDQYGS  60
   61 QYGGPYGQPY DHYGSRGSMG RRSIGSARNP GNGSPEPPPP PPRNHDM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1939-2017]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNSSFNDSKE SNEISEAECD RDHGPRGNYG AVKRSPQPKD QRTTEEMRKL IERNETGPKQ  60
   61 LQLQQANGAG FTAYDTMAV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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