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View Structure Prediction Details

Protein: CG9935-PC
Organism: Drosophila melanogaster
Length: 871 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG9935-PC.

Description E-value Query
Range
Subject
Range
GRIK2_MOUSE, GLK... - (P39087) Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) ...
547.0 [0..6] [860..19]

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Predicted Domain #1
Region A:
Residues: [1-498]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIASGFLLF QFLSYGLGVP PLVRIGAIFS NQPGMYNSEL AFRYAIHRLN MDKSLLPETT  60
   61 VDYYVEYVNR FDSFETVQKV CKLIRVGVQA VFSPTDSVLA THINSICDAL DIPNIGRSAH 120
  121 DFSINVYPSK QLVNYAFNDV IQYLNWTRFG ILHEKENGII NLHQLSRSFH GEVHMRQVSR 180
  181 DSYVSALNEF KGKEIHNIII DTNSNGISIL LKNILQQQMN EYKYHYLFTS FDLETYDLED 240
  241 FKYNFVNITS FRLVDTADVG VKQILKDIGL YSHHIFKKPY LNLHIKKSTI LESEPALMFD 300
  301 SVYVFAIGLQ TLEQSHSLTL LNISCEEENS WDGGLSLINY LNAVEWKGLT GPIQFKDGQR 360
  361 VQFKLDLIKL KQHSIVKVGE WTPHGHLNIT EPSMFFDAGS MNVTLVVITI LETPYVMMHY 420
  421 GKNFTGNERF YGFCVDILET ISREVGFDYI LDLVPDRKYG AKDPETGEWN GMVAQLMKYK 480
  481 ADLAVGSMTI TYARESVI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.0
Match: 2e4uA
Description: No description for 2e4uA was found.

Predicted Domain #2
Region A:
Residues: [499-629]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFTKPFMNLG ISILFKVPTS EPTRLFSFMN PLAIEIWIYV LIAYFLVSLC IYIVGKLSPI  60
   61 EWKCINACDL ENISIGNQFS LTDSFWFTIG TFMQQSPDIY PRAMSTRIIS STWGFFSLII 120
  121 VASYTANLAA F

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.3
Match: 1xl4A
Description: Intermediate gating structure 1 of the inwardly rectifying K+ channel KirBac3.1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
gated channel activity 3.69159251802076 bayes_pls_golite062009
voltage-gated potassium channel activity 3.44021953730907 bayes_pls_golite062009
potassium channel activity 3.390404838627 bayes_pls_golite062009
voltage-gated cation channel activity 3.03335269249917 bayes_pls_golite062009
voltage-gated ion channel activity 2.97559865523675 bayes_pls_golite062009
substrate-specific channel activity 2.97010589436002 bayes_pls_golite062009
channel activity 2.96709641892817 bayes_pls_golite062009
passive transmembrane transporter activity 2.96709641892817 bayes_pls_golite062009
voltage-gated channel activity 2.95293713789301 bayes_pls_golite062009
cation channel activity 2.93137972840708 bayes_pls_golite062009
ion channel activity 2.90649323275732 bayes_pls_golite062009
metal ion transmembrane transporter activity 2.79927269240187 bayes_pls_golite062009
transporter activity 2.77619896060397 bayes_pls_golite062009
transmembrane transporter activity 2.65613366364107 bayes_pls_golite062009
substrate-specific transporter activity 2.60593795082679 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.51155410430955 bayes_pls_golite062009
ion transmembrane transporter activity 2.43226648492335 bayes_pls_golite062009
ligand-gated ion channel activity 2.41007732307954 bayes_pls_golite062009
ligand-gated channel activity 2.41007732307954 bayes_pls_golite062009
cation transmembrane transporter activity 2.36191716490754 bayes_pls_golite062009
inward rectifier potassium channel activity 1.02042603980667 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [630-871]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTTERMINPI ENAEDLASQT EISYGTLDSG STMTFFRDSV IETYKKIWRS MDNKKPSAFT  60
   61 TTYEDGIKRV NQGNYAFLME STMLDYIVQR DCNLTQIGGL LDTKGYGIAT PKGSPWRDKI 120
  121 SLAILELQER GDIQMLYDKW WKNTDETCTR KNTSKQSKAN SLGLESIGGV FVVLIAGIIV 180
  181 AAVVAFFEFC ERNYTPPDRS FWIEIAEELR YASWCMNKQK RPALTRTCSK CTIPKGQRIN 240
  241 KL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.522879
Match: 1yaeA
Description: Structure of the Kainate Receptor Subunit GluR6 Agonist Binding Domain Complexed with Domoic Acid
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle