YRC Public Data Repository - Protein Structure Prediction

Protein:	COPE
Organism:	Homo sapiens
Length:	308 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COPE.

Description	E-value	Query Range	Subject Range
gi\|46119251, gi\|... - gi\|67923685\|ref\|ZP_00517153.1\| TPR repeat:TPR repeat [Crocosphaera watsonii WH 8501], gi\|67854485\|gb...	2.0E-45	[21..296]	[248..526]
gi\|71675440, gi\|... - gi\|71675440\|ref\|ZP_00673185.1\| TPR repeat:Sel1-like repeat [Trichodesmium erythraeum IMS101], gi\|716...	3.0E-45	[14..307]	[992..1291]
PP385_ARATH - Pentatricopeptide repeat-containing protein At5g15300 OS=Arabidopsis thaliana GN=PCMP-E40 PE=2 SV=2	3.0E-45	[17..303]	[147..432]
gi\|41719589, gi\|... - gi\|91774230\|ref\|YP_566922.1\| tetratricopeptide protein [Methanococcoides burtonii DSM 6242], gi\|9171...	1.0E-44	[35..306]	[196..473]
gi\|7459510 - pir\|\|B69196 conserved hypothetical protein MTH72 - Methanobacterium thermoautotrophicum (strain Delt... gi\|15678100, gi\|... - gi\|2621106\|gb\|AAB84576.1\| O-linked GlcNAc transferase [Methanothermobacter thermautotrophicus str. D...	1.0E-44	[9..307]	[12..314]

Back

Predicted Domain #1

Region A:
Residues: [1-308]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPPAPGPAS GGSGEVDELF DVKNAFYIGS YQQCINEAQR VKLSSPERDV ERDVFLYRAY  60
   61 LAQRKFGVVL DEIKPSSAPE LQAVRMFADY LAHESRRDSI VAELDREMSR SVDVTNTTFL 120
  121 LMAASIYLHD QNPDAALRAL HQGDSLECTA MTVQILLKLD RLDLARKELK RMQDLDEDAT 180
  181 LTQLATAWVS LATGGEKLQD AYYIFQEMAD KCSPTLLLLN GQAACHMAQG RWEAAEGLLQ 240
  241 EALDKDSGYP ETLVNLIVLS QHLGKPPEVT NRYLSQLKDA HRSHPFIKEY QAKENDFDRL 300
  301 VLQYAPSA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.522879
Match:	1w3bA
Description:	The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.09193012129784	bayes_pls_golite062009
protein binding	1.52807685989528	bayes_pls_golite062009
signal sequence binding	1.13935627118933	bayes_pls_golite062009
peroxisome targeting sequence binding	0.69717675806841	bayes_pls_golite062009
syntaxin binding	0.0598606763736398	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: