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View Structure Prediction Details

Protein: gi|14043299
Organism: Homo sapiens
Length: 310 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|14043299.

Description E-value Query
Range
Subject
Range
gi|89191850, gi|... - gi|89191850|ref|NP_001034762.1| Yip1 interacting factor homolog B isoform 4 [Homo sapiens], gi|11957...
0.0 [1..310] [2..311]
gi|55649015 - gi|55649015|ref|XP_512634.1| PREDICTED: Yip1 interacting factor homolog B isoform 5 [Pan troglodytes...
0.0 [1..310] [2..311]
gi|158937260, gi... - gi|80477099|gb|AAI09332.1| Yif1b protein [Mus musculus], ref|XP_284281.2| RIKEN cDNA 9430029K10 [Mus...
0.0 [1..310] [2..308]
gi|73947763 - gi|73947763|ref|XP_541646.2| PREDICTED: similar to Yip1 interacting factor homolog B isoform a isofo...
0.0 [1..310] [2..309]
gi|62388883, gi|... - gi|62388883|ref|NP_942029.2| Yip1 interacting factor homolog B isoform a [Rattus norvegicus], gi|149...
0.0 [1..310] [2..311]

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Predicted Domain #1
Region A:
Residues: [1-240]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPAGLAAAAA GTPRLPSKRR IPVSQPGMAD PHQLFDDTSS AQSRGYGAQR APGGLSYPAA  60
   61 SPTPHAAFLA DPVSNMAMAY GSSLAAQGKE LVDKNIDRFI PITKLKYYFA VDTMYVGRKL 120
  121 GLLFFPYLHQ DWEVQYQQDT PVAPRFDVNA PDLYIPAMAF ITYVLVAGLA LGTQDRFSPD 180
  181 LLGLQASSAL AWLTLEVLAI LLSLYLVTVN TDLTTIDLVA FLGYKYVGMI GGVLMGLLFG 240
  241 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.976
Match: 1dx0A
Description: Prion protein domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.22514585792228 bayes_pls_golite062009
tubulin binding 1.96726329576357 bayes_pls_golite062009
protein binding 1.76565398252144 bayes_pls_golite062009
cytoskeletal protein binding 1.71860571490508 bayes_pls_golite062009
microtubule binding 1.7070745359784 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [241-310]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIGYYLVLGW CCVAIFVFMI RTLRLKILAD AAAEGVPVRG ARNQLRMYLT MAVAAAQPML  60
   61 MYWLTFHLVR 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle