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View Structure Prediction Details

Protein: BTN3A2
Organism: Homo sapiens
Length: 334 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BTN3A2.

Description E-value Query
Range
Subject
Range
gi|8515716 - gi|8515716|gb|AAF76140.1|AF257505_1 butyrophilin, subfamily 3, member A2 [Homo sapiens]
3.0E-49 [1..334] [1..334]
gi|114605814, gi... - gi|114605818|ref|XP_001173286.1| PREDICTED: butyrophilin, subfamily 3, member A3 isoform 7 [Pan trog...
3.0E-48 [1..328] [1..328]
gi|109069963, gi... - gi|109069967|ref|XP_001091158.1| PREDICTED: similar to butyrophilin, subfamily 3, member A3 isoform ...
6.0E-47 [1..328] [1..328]
BT3A3_PONPY - Butyrophilin subfamily 3 member A3 precursor - Pongo pygmaeus (Orangutan)
BT3A3_PONAB - Butyrophilin subfamily 3 member A3 OS=Pongo abelii GN=BTN3A3 PE=2 SV=1
8.0E-45 [1..328] [1..328]

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Predicted Domain #1
Region A:
Residues: [1-146]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKMASSLAFL LLNFHVSLLL VQLLTPCSAQ FSVLGPSGPI LAMVGEDADL PCHLFPTMSA  60
   61 ETMELKWVSS SLRQVVNVYA DGKEVEDRQS APYRGRTSIL RDGITAGKAA LRIHNVTASD 120
  121 SGKYLCYFQD GDFYEKALVE LKVAAL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.0
Match: 1py9A
Description: The crystal structure of an autoantigen in multiple sclerosis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
antigen binding 3.16266926144655 bayes_pls_golite062009
binding 2.27505133637052 bayes_pls_golite062009
protein binding 1.97297990316681 bayes_pls_golite062009
receptor activity 0.191524908565499 bayes_pls_golite062009
signal transducer activity 0.0925371302972207 bayes_pls_golite062009
molecular transducer activity 0.0925371302972207 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [147-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSNLHVEVKG YEDGGIHLEC RSTGWYPQPQ IQWSNAKGEN IPAVEAPVVA DGVGLYEVAA  60
   61 SVIMRGGSGE GVSCIIRNSL LGLEKTASIS IADPFFRSAQ PWIAALAGTL PILLLLLAGA 120
  121 SYFLWRQQKE ITALSSEIES EQEMKEMGYA ATEREISLRE SLQEELKRKK IQYLTRGEES 180
  181 SSDTNKSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.39794
Match: 1ya5A
Description: Crystal structure of the titin domains z1z2 in complex with telethonin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle