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View Structure Prediction Details

Protein: HNRNPR
Organism: Homo sapiens
Length: 633 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HNRNPR.

Description E-value Query
Range
Subject
Range
gi|114554622 - gi|114554622|ref|XP_513191.2| PREDICTED: similar to heterogeneous nuclear ribonucleoprotein R [Pan t...
2.0E-66 [1..633] [106..738]
gi|55732180 - gi|55732180|emb|CAH92794.1| hypothetical protein [Pongo abelii]
gi|197102464 - gi|197102464|ref|NP_001126631.1| heterogeneous nuclear ribonucleoprotein R [Pongo abelii]
2.0E-66 [1..633] [1..633]
gi|108999072 - gi|108999072|ref|XP_001111802.1| PREDICTED: heterogeneous nuclear ribonucleoprotein R [Macaca mulatt...
2.0E-65 [1..633] [161..793]
gi|74207436 - gi|74207436|dbj|BAE30898.1| unnamed protein product [Mus musculus]
2.0E-65 [1..633] [1..632]
gi|12655185, gi|... - gi|56203530|emb|CAI19027.1| heterogeneous nuclear ribonucleoprotein R [Homo sapiens], gi|156151394|r...
gi|123997373, gi... - gi|123997373|gb|ABM86288.1| heterogeneous nuclear ribonucleoprotein R [synthetic construct], gi|1239...
ENSPTRT00000000644 - null
2.0E-65 [1..633] [1..636]
gi|62990189, gi|... - gi|62990189|ref|NP_783193.2| heterogeneous nuclear ribonucleoprotein R [Rattus norvegicus], gi|62471...
3.0E-65 [1..633] [1..632]

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Predicted Domain #1
Region A:
Residues: [1-158]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANQVNGNAV QLKEEEEPMD TSSVTHTEHY KTLIEAGLPQ KVAERLDEIF QTGLVAYVDL  60
   61 DERAIDALRE FNEEGALSVL QQFKESDLSH VQNKSAFLCG VMKTYRQREK QGSKVQESTK 120
  121 GPDEAKIKAL LERTGYTLDV TTGQRKYGGP PPDSVYSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [159-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQPGIGTEVF VGKIPRDLYE DELVPLFEKA GPIWDLRLMM DPLSGQNRGY AFITFCGKEA  60
   61 AQEAVKLCDS YEIRPGKHLG VCISVANNRL FVG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 2dguA
Description: No description for 2dguA was found.

Predicted Domain #3
Region A:
Residues: [252-426]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIPKNKTKEN ILEEFSKVTE GLVDVILYHQ PDDKKKNRGF CFLEYEDHKS AAQARRRLMS  60
   61 GKVKVWGNVV TVEWADPVEE PDPEVMAKVK VLFVRNLATT VTEEILEKSF SEFGKLERVK 120
  121 KLKDYAFVHF EDRGAAVKAM DEMNGKEIEG EEIEIVLAKP PDKKRKERQA ARQAS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.29
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.787118623292657 bayes_pls_golite062009
nucleic acid binding 0.0269483316710413 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [427-633]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSTAYEDYYY HPPPRMPPPI RGRGRGGGRG GYGYPPDYYG YEDYYDDYYG YDYHDYRGGY  60
   61 EDPYYGYDDG YAVRGRGGGR GGRGAPPPPR GRGAPPPRGR AGYSQRGAPL GPPRGSRGGR 120
  121 GGPAQQQRGR GSRGSRGNRG GNVGGKRKAD GYNQPDSKRR QTNNQQNWGS QPIAQQPLQQ 180
  181 GGDYSGNYGY NNDNQEFYQD TYGQQWK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle