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View Structure Prediction Details

Protein: gi|870745, gi|18...
Organism: Homo sapiens
Length: 306 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|870745, gi|18....

Description E-value Query
Range
Subject
Range
gi|13560783 - gi|13560783|gb|AAK30205.1|AF349964_1 poly(A)-binding protein [Daucus carota]
2.0E-49 [10..304] [138..444]
PABP2_ARATH - Polyadenylate-binding protein 2 OS=Arabidopsis thaliana GN=PAB2 PE=1 SV=1
2.0E-48 [9..304] [133..440]
gi|92873940 - gi|92873940|gb|ABE82276.1| RNA-binding region RNP-1 (RNA recognition motif) [Medicago truncatula]
3.0E-48 [11..304] [133..438]
gi|7673355 - gi|7673355|gb|AAF66823.1|AF190655_1 poly(A)-binding protein [Nicotiana tabacum]
4.0E-48 [11..304] [126..431]
gi|76689279 - gi|76689279|ref|XP_881322.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
1.0E-47 [10..305] [109..424]
gi|73976781 - gi|73976781|ref|XP_857374.1| PREDICTED: similar to Polyadenylate-binding protein 4 (Poly(A)-binding ...
3.0E-47 [10..305] [109..427]
gi|48734702 - gi|48734702|gb|AAH71591.1| PABPC4 protein [Homo sapiens]
3.0E-47 [10..305] [109..425]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEEQFGGDG AAAAATAAVG GSAGEQEGAM VAATQGAAAA AGSGAGTGGG TASGGTEGGS  60
   61 AESEGAKIDA SKNEEDEGHS NSSPRHSE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.0
Match: 2dhsA
Description: No description for 2dhsA was found.

Predicted Domain #2
Region A:
Residues: [89-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AATAQREEWK MFIGGLSWDT TKKDLKDYFS KFGEVVDCTL KLDPITGRSR GFGFVLFKES  60
   61 ESVDKVMDQK EHKLNGKVID PKRAKAMKTK EPVKKIFVGG LSPDTPEEKI REYFGGFGEV 120
  121 ESIELPMDNK TNKRRGFCFI TFKEEEPVKK IMEKKYHNVG LSKCEIKVAM SKEQYQQQQQ 180
  181 WGSRGGFAGR ARGRGGDQQS GYGKVSRRGG HQNSYKPY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.39794
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
snRNA binding 3.28448936696877 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
U1 snRNA binding 2.26303528058407 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
protein binding 2.17260848225967 bayes_pls_golite062009
DNA binding 1.98418556946403 bayes_pls_golite062009
sequence-specific DNA binding 1.48484912902372 bayes_pls_golite062009
structural molecule activity 1.40416767516887 bayes_pls_golite062009
transcription activator activity 1.2789602751031 bayes_pls_golite062009
transcription factor activity 1.07843408116687 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle