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View Structure Prediction Details

Protein: gi|119626279, gi...
Organism: Homo sapiens
Length: 336 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|119626279, gi....

Description E-value Query
Range
Subject
Range
gi|73976797 - gi|73976797|ref|XP_857696.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
5.0E-52 [2..326] [115..460]
gi|76689281 - gi|76689281|ref|XP_881384.1| PREDICTED: similar to Polyadenylate-binding protein 4 (Poly(A)-binding ...
5.0E-52 [2..326] [115..463]
gi|41388837 - gi|41388837|gb|AAH65540.1| PABPC4 protein [Homo sapiens]
1.0E-51 [2..326] [115..460]

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Predicted Domain #1
Region A:
Residues: [1-73]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEEQFGGDG AAAAATAAVG GSAGEQEGAM VAATQGAAAA AGSGAGTGGG TASGGTEGGS  60
   61 AESEGAKIDA SKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.0
Match: 2dhsA
Description: No description for 2dhsA was found.

Predicted Domain #2
Region A:
Residues: [74-245]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEDEGKMFIG GLSWDTTKKD LKDYFSKFGE VVDCTLKLDP ITGRSRGFGF VLFKESESVD  60
   61 KVMDQKEHKL NGKVIDPKRA KAMKTKEPVK KIFVGGLSPD TPEEKIREYF GGFGEVESIE 120
  121 LPMDNKTNKR RGFCFITFKE EEPVKKIMEK KYHNVGLSKC EIKVAMSKEQ YQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.221849
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [246-336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQQQWGSRGG FAGRARGRGG GPSQNWNQGY SNYWNQGYGN YGYNSQGYGG YGGYDYTGYN  60
   61 NYYGYGDYSN QQSGYGKVSR RGGHQNSYKP Y

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle