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View Structure Prediction Details

Protein: HNRPD
Organism: Homo sapiens
Length: 355 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HNRPD.

Description E-value Query
Range
Subject
Range
gi|73976797 - gi|73976797|ref|XP_857696.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
8.0E-51 [9..350] [108..464]
gi|76689279 - gi|76689279|ref|XP_881322.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
2.0E-50 [9..350] [108..463]
gi|55959640, gi|... - gi|55962218|emb|CAI12299.1| poly(A) binding protein, cytoplasmic 4 (inducible form) [Homo sapiens], ...
3.0E-50 [9..346] [108..460]

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Predicted Domain #1
Region A:
Residues: [1-83]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEEQFGGDG AAAAATAAVG GSAGEQEGAM VAATQGAAAA AGSGAGTGGG TASGGTEGGS  60
   61 AESEGAKIDA SKNEEDEGHS NSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.0
Match: 1qm9A
Description: Polypyrimidine tract-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [84-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRHSEAATAQ REEWKMFIGG LSWDTTKKDL KDYFSKFGEV VDCTLKLDPI TGRSRGFGFV  60
   61 LFKESESVDK VMDQKEHKLN GKVIDPKRAK AMKTKEPVKK IFVGGLSPDT PEEKIREYFG 120
  121 GFGEVESIEL PMDNKTNKRR GFCFITFKEE EPVKKIMEKK YHNVGLSKCE IKVAMSKEQY 180
  181 QQQQQWGSRG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.154902
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [274-355]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GFAGRARGRG GGPSQNWNQG YSNYWNQGYG NYGYNSQGYG GYGGYDYTGY NNYYGYGDYS  60
   61 NQQSGYGKVS RRGGHQNSYK PY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle