YRC Public Data Repository - Protein Structure Prediction

Protein:	ALG14
Organism:	Homo sapiens
Length:	216 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ALG14.

Description	E-value	Query Range	Subject Range
ALG14_RAT - UDP-N-acetylglucosamine transferase subunit ALG14 homolog OS=Rattus norvegicus GN=Alg14 PE=2 SV=1	2.0E-51	[1..216]	[1..216]
gi\|109011359 - gi\|109011359\|ref\|XP_001103820.1\| PREDICTED: similar to asparagine-linked glycosylation 14 homolog [M...	4.0E-50	[1..216]	[1..216]
ALG14_MOUSE - UDP-N-acetylglucosamine transferase subunit ALG14 homolog OS=Mus musculus GN=Alg14 PE=1 SV=1	6.0E-50	[1..216]	[1..217]
MURG_HAES1 - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosam...	1.0E-47	[33..216]	[2..161]
gi\|77962098 - gi\|77962098\|ref\|ZP_00825923.1\| COG0707: UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase ...	6.0E-47	[31..216]	[1..162]
gi\|77958235 - gi\|77958235\|ref\|ZP_00822272.1\| COG0707: UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase ...	1.0E-46	[31..216]	[1..162]
gi\|91187948, gi\|... - gi\|91228514\|ref\|ZP_01262436.1\| N-acetylglucosaminyl transferase [Vibrio alginolyticus 12G01], gi\|911...	1.0E-46	[31..216]	[1..161]
MURG_VIBF1 - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosam...	1.0E-46	[31..216]	[1..162]
MURG_PASMU - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosam... MURG_PASMU - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosam...	2.0E-46	[31..216]	[1..162]
gi\|77976100 - gi\|77976100\|ref\|ZP_00831633.1\| COG0707: UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase ...	2.0E-46	[31..216]	[1..162]

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Predicted Domain #1

Region A:
Residues: [1-216]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVCVLVLAAA AGAVAVFLIL RIWVVLRSMD VTPRESLSIL VVAGSGGHTT EILRLLGSLS  60
   61 NAYSPRHYVI ADTDEMSANK INSFELDRAD RDPSNMYTKY YIHRIPRSRE VQQSWPSTVF 120
  121 TTLHSMWLSF PLIHRVKPDL VLCNGPGTCV PICVSALLLG ILGIKKVIIV YVESICRVET 180
  181 LSMSGKILFH LSDYFIVQWP ALKEKYPKSV YLGRIV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.522879
Match:	1f0kA
Description:	Peptidoglycan biosynthesys glycosyltransferase MurG
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glycolipid mannosyltransferase activity	4.60562208522558	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	3.70184884300914	bayes_pls_golite062009
mannosyltransferase activity	3.21859657603001	bayes_pls_golite062009
catalytic activity	2.65148466065976	bayes_pls_golite062009
transferase activity	2.6268567881241	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.62403914335522	bayes_pls_golite062009
alpha-1,3-mannosyltransferase activity	2.61939274100154	bayes_pls_golite062009
UDP-glycosyltransferase activity	2.13085705769565	bayes_pls_golite062009
alpha-1,6-mannosyltransferase activity	2.10015128523477	bayes_pls_golite062009
glycolipid 3-alpha-mannosyltransferase activity	2.10015128523477	bayes_pls_golite062009
glycolipid 6-alpha-mannosyltransferase activity	2.10015128523477	bayes_pls_golite062009
protein anchor	1.99520345594672	bayes_pls_golite062009
glucosyltransferase activity	1.5162351691061	bayes_pls_golite062009
UDP-glucosyltransferase activity	1.21599854394093	bayes_pls_golite062009
glycogen phosphorylase activity	0.607220464589157	bayes_pls_golite062009
binding	0.399722153246393	bayes_pls_golite062009
acetylglucosaminyltransferase activity	0.354187614795831	bayes_pls_golite062009
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	0.333194028937286	bayes_pls_golite062009
phosphorylase activity	0.296436712681472	bayes_pls_golite062009
protein binding	0.159157411441002	bayes_pls_golite062009
carbohydrate phosphatase activity	4.32270241054966E-4	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: