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View Structure Prediction Details

Protein: SSRP1
Organism: Homo sapiens
Length: 709 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SSRP1.

Description E-value Query
Range
Subject
Range
SSRP1_RAT - FACT complex subunit SSRP1 OS=Rattus norvegicus GN=Ssrp1 PE=1 SV=2
0.0 [1..709] [1..709]
SSRP1_MOUSE - FACT complex subunit SSRP1 OS=Mus musculus GN=Ssrp1 PE=1 SV=2
0.0 [1..709] [1..708]
gi|109106294 - gi|109106294|ref|XP_001103334.1| PREDICTED: similar to structure specific recognition protein 1 [Mac...
0.0 [1..709] [1..709]
gi|73982281 - gi|73982281|ref|XP_849848.1| PREDICTED: similar to structure specific recognition protein 1 isoform ...
0.0 [1..709] [1..708]
gi|8170740 - gi|8170740|gb|AAB19500.2| HMG1-related DNA-binding protein [Mus sp.]
SSRP_MOUSE, SSRP... - (Q08943) Structure-specific recognition protein 1 (SSRP1) (Recombination signal sequence recognition...
0.0 [1..709] [1..708]
gi|60552474 - gi|60552474|gb|AAH91486.1| SSRP1 protein [Homo sapiens]
0.0 [1..615] [1..615]

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Predicted Domain #1
Region A:
Residues: [1-169]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAETLEFNDV YQEVKGSMND GRLRLSRQGI IFKNSKTGKV DNIQAGELTE GIWRRVALGH  60
   61 GLKLLTKNGH VYKYDGFRES EFEKLSDFFK THYRLELMEK DLCVKGWNWG TVKFGGQLLS 120
  121 FDIGDQPVFE IPLSNVSQCT TGKNEVTLEF HQNDDAEVSL MEVRFYVPP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [170-427]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQEDGVDPVE AFAQNVLSKA DVIQATGDAI CIFRELQCLT PRGRYDIRIY PTFLHLHGKT  60
   61 FDYKIPYTTV LRLFLLPHKD QRQMFFVISL DPPIKQGQTR YHFLILLFSK DEDISLTLNM 120
  121 NEEEVEKRFE GRLTKNMSGS LYEMVSRVMK ALVNRKITVP GNFQGHSGAQ CITCSYKASS 180
  181 GLLYPLERGF IYVHKPPVHI RFDEISFVNF ARGTTTTRSF DFEIETKQGT QYTFSSIERE 240
  241 EYGKLFDFVN AKKLNIKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.522879
Match: 2gcjA
Description: No description for 2gcjA was found.

Predicted Domain #3
Region A:
Residues: [428-538]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGLKEGMNPS YDEYADSDED QHDAYLERMK EEGKIREENA NDSSDDSGEE TDESFNPGEE  60
   61 EEDVAEEFDS NASASSSSNE GDSDRDEKKR KQLKKAKMAK DRKSRKKPVE V

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [539-709]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKGKDPNAPK RPMSAYMLWL NASREKIKSD HPGISITDLS KKAGEIWKGM SKEKKEEWDR  60
   61 KAEDARRDYE KAMKEYEGGR GESSKRDKSK KKKKVKVKME KKSTPSRGSS SKSSSRQLSE 120
  121 SFKSKEFVSS DESSSGENKS KKKRRRSEDS EEEELASTPP SSEDSASGSD E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.221849
Match: 2gzkA
Description: No description for 2gzkA was found.

Predicted functions:

Term Confidence Notes
DNA binding 5.15324651287773 bayes_pls_golite062009
nucleic acid binding 5.01228762819617 bayes_pls_golite062009
transcription regulator activity 4.9607192917135 bayes_pls_golite062009
transcription factor activity 3.82658263870186 bayes_pls_golite062009
binding 3.6211482127468 bayes_pls_golite062009
transcription repressor activity 3.17018042329608 bayes_pls_golite062009
sequence-specific DNA binding 2.96229555092695 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.75319687398598 bayes_pls_golite062009
transcription activator activity 1.62744929149746 bayes_pls_golite062009
structure-specific DNA binding 1.51189746794562 bayes_pls_golite062009
protein binding 1.131658134984 bayes_pls_golite062009
transcription factor binding 1.10315330167937 bayes_pls_golite062009
chromatin binding 0.996049314969019 bayes_pls_golite062009
DNA bending activity 0.87985209274756 bayes_pls_golite062009
specific transcriptional repressor activity 0.4255419067266 bayes_pls_golite062009
single-stranded DNA binding 0.392549154964715 bayes_pls_golite062009
open form four-way junction DNA binding 0.293183929205961 bayes_pls_golite062009
bent DNA binding 0.293183929205961 bayes_pls_golite062009
crossed form four-way junction DNA binding 0.293183929205961 bayes_pls_golite062009
DNA secondary structure binding 0.18003196535795 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.0654173145582195 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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