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View Structure Prediction Details

Protein: MATR3
Organism: Homo sapiens
Length: 847 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MATR3.

Description E-value Query
Range
Subject
Range
gi|114602033, gi... - gi|114602033|ref|XP_001172359.1| PREDICTED: matrin 3 isoform 12 [Pan troglodytes], gi|114602031|ref|...
0.0 [1..847] [1..847]
gi|40788339 - gi|40788339|dbj|BAA34443.2| KIAA0723 protein [Homo sapiens]
0.0 [1..847] [7..853]
gi|34878612, gi|... - gi|62664153|ref|XP_579423.1| PREDICTED: hypothetical protein XP_579423 [Rattus norvegicus], gi|61889...
0.0 [1..847] [1..845]
gi|109078824, gi... - gi|109078826|ref|XP_001114358.1| PREDICTED: matrin 3 isoform 7 [Macaca mulatta], gi|109078824|ref|XP...
0.0 [1..847] [1..847]
gi|197101369 - gi|197101369|ref|NP_001126563.1| matrin 3 isoform 1 [Pongo abelii]
gi|55731929 - gi|55731929|emb|CAH92673.1| hypothetical protein [Pongo abelii]
0.0 [1..847] [1..847]
MATR3_MOUSE - Matrin-3 OS=Mus musculus GN=Matr3 PE=1 SV=1
0.0 [1..847] [1..846]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKSFQQSSL SRDSQGHGRD LSAAGIGLLA AATQSLSMPA SLGRMNQGTA RLASLMNLGM  60
   61 SSSLNQQGAH SALSSASTSS HNLQSIFNIG SRGPL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [96-167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLSSQHRGDA DQASNILASF GLSARDLDEL SRYPEDKITP ENLPQILLQL KRRRTEEGPT  60
   61 LSYGRDGRSA TR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [168-375]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPPYRVPRDD WEEKRHFRRD SFDDRGPSLN PVLDYDHGSR SQESGYYDRM DYEDDRLRDG  60
   61 ERCRDDSFFG ETSHNYHKFD SEYERMGRGP GPLQERSLFE KKRGAPPSSN IEDFHGLLPK 120
  121 GYPHLCSICD LPVHSNKEWS QHINGASHSR RCQLLLEIYP EWNPDNDTGH TMGDPFMLQQ 180
  181 STNPAPGILG PPPPSFHLGG PAVGPRGN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [376-472]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGAGNGNLQG PRHMQKGRVE TSRVVHIMDF QRGKNLRYQL LQLVEPFGVI SNHLILNKIN  60
   61 EAFIEMATTE DAQAAVDYYT TTPALVFGKP VRVHLSQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.0
Match: 1x4fA
Description: Solution structure of the second RRM domain in Matrin 3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.26550630643712 bayes_pls_golite062009
nucleic acid binding 2.02897811404491 bayes_pls_golite062009
RNA binding 1.45577328897026 bayes_pls_golite062009
mRNA binding 0.274978159646657 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [473-596]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYKRIKKPEG KPDQKFDQKQ ELGRVIHLSN LPHSGYSDSA VLKLAEPYGK IKNYILMRMK  60
   61 SQAFIEMETR EDAMAMVDHC LKKALWFQGR CVKVDLSEKY KKLVLRIPNR GIDLLKKDKS 120
  121 RKRS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.23
Match: 1x4fA
Description: Solution structure of the second RRM domain in Matrin 3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.10183662096756 bayes_pls_golite062009
nucleic acid binding 1.76030419422519 bayes_pls_golite062009
RNA binding 1.04699342909932 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [597-661]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YSPDGKESPS DKKSKTDGSQ KTESSTEGKE QEEKSGEDGE KDTKDDQTEQ EPNMLLESED  60
   61 ELLVD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [662-847]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEEAAALLES GSSVGDETDL ANLGDVASDG KKEPSDKAVK KDGSASAAAK KKLKKVDKIE  60
   61 ELDQENEAAL ENGIKNEENT EPGAESSENA DDPNKDTSEN ADGQSDENKD DYTIPDEYRI 120
  121 GPYQPNVPVG IDYVIPKTGF YCKLCSLFYT NEEVAKNTHC SSLPHYQKLK KFLNKLAEER 180
  181 RQKKET

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle