YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: PPP2R5D
Organism: Homo sapiens
Length: 602 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PPP2R5D.

Description E-value Query
Range
Subject
Range
gi|109486753, gi... - gi|109486753|ref|XP_001065844.1| PREDICTED: similar to delta isoform of regulatory subunit B56, prot...
0.0 [1..602] [67..661]
gi|148691584, gi... - gi|74180345|dbj|BAE32340.1| unnamed protein product [Mus musculus], gi|74141162|dbj|BAE35894.1| unna...
0.0 [1..602] [1..594]
gi|114607473 - gi|114607473|ref|XP_518483.2| PREDICTED: delta isoform of regulatory subunit B56, protein phosphatas...
0.0 [1..602] [67..668]
gi|73972846 - gi|73972846|ref|XP_538927.2| PREDICTED: similar to delta isoform of regulatory subunit B56, protein ...
0.0 [1..602] [1..602]
gi|115304937 - gi|115304937|gb|AAI23870.1| PPP2R5D protein [Bos taurus]
0.0 [1..602] [20..619]
2A5D_RABIT - Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform OS=Oryctolagus cunic...
0.0 [18..602] [2..586]

Back

Predicted Domain #1
Region A:
Residues: [1-99]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPYKLKKEKE PPKVAKCTAK PSSSGKDGGG ENTEEAQPQP QPQPQPQAQS QPPSSNKRPS  60
   61 NSTPPPTQLS KIKYSGGPQI VKKERRQSSS RFNLSKNRE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [100-532]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQKLPALKDS PTQEREELFI QKLRQCCVLF DFVSDPLSDL KFKEVKRAGL NEMVEYITHS  60
   61 RDVVTEAIYP EAVTMFSVNL FRTLPPSSNP TGAEFDPEED EPTLEAAWPH LQLVYEFFLR 120
  121 FLESPDFQPN IAKKYIDQKF VLALLDLFDS EDPRERDFLK TILHRIYGKF LGLRAYIRRQ 180
  181 INHIFYRFIY ETEHHNGIAE LLEILGSIIN GFALPLKEEH KMFLIRVLLP LHKVKSLSVY 240
  241 HPQLAYCVVQ FLEKESSLTE PVIVGLLKFW PKTHSPKEVM FLNELEEILD VIEPSEFSKV 300
  301 MEPLFRQLAK CVSSPHFQVA ERALYYWNNE YIMSLISDNA ARVLPIMFPA LYRNSKSHWN 360
  361 KTIHGLIYNA LKLFMEMNQK LFDDCTQQYK AEKQKGRFRM KEREEMWQKI EELARLNPQY 420
  421 PMFRAPPPLP PVY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 2nppB
Description: No description for 2nppB was found.

Predicted functions:

Term Confidence Notes
binding 3.0667965351474 bayes_pls_golite062009
protein serine/threonine phosphatase activity 2.90442709223348 bayes_pls_golite062009
phosphoprotein phosphatase activity 2.43818477885422 bayes_pls_golite062009
protein phosphatase type 2A regulator activity 2.4262941420561 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.13472456858224 bayes_pls_golite062009
phosphatase regulator activity 1.88919819318597 bayes_pls_golite062009
protein phosphatase regulator activity 1.7842476658781 bayes_pls_golite062009
protein binding 1.73688475473996 bayes_pls_golite062009
phosphatase activity 1.47453833246612 bayes_pls_golite062009
phosphoric ester hydrolase activity 1.24670233688276 bayes_pls_golite062009
myosin phosphatase activity 1.2020405346133 bayes_pls_golite062009
nucleic acid binding 1.13208464017585 bayes_pls_golite062009
hydrolase activity 0.42501390959416 bayes_pls_golite062009
transcription regulator activity 0.385452858197632 bayes_pls_golite062009
DNA binding 0.309260217284589 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [533-602]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SMETETPTAE DIQLLKRTVE TEAVQMLKDI KKEKVLLRRK SELPQDVYTI KALEAHKRAE  60
   61 EFLTASQEAL 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle