YRC Public Data Repository - Protein Structure Prediction

Protein:	MAGED2
Organism:	Homo sapiens
Length:	606 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MAGED2.

Description	E-value	Query Range	Subject Range
gi\|12659136 - gi\|12659136\|gb\|AAK01204.1\| mage-d2 [Mus musculus]	445.0	[0..1]	[606..1]
MAGD2_PONPY - Melanoma-associated antigen D2 - Pongo pygmaeus (Orangutan) MAGD2_PONAB - Melanoma-associated antigen D2 OS=Pongo abelii GN=MAGED2 PE=2 SV=1	436.0	[0..1]	[606..1]
gi\|4099969 - gi\|4099969\|gb\|AAD00728.1\| hepatocellular carcinoma associated protein [Homo sapiens]	434.0	[0..1]	[606..1]
gi\|109130890, gi... - gi\|109130894\|ref\|XP_001091552.1\| PREDICTED: melanoma antigen family D, 2 isoform 6 [Macaca mulatta],...	431.0	[0..1]	[606..1]
gi\|149031333, gi... - gi\|78042585\|ref\|NP_536727.2\| melanoma antigen family D, 2 [Rattus norvegicus], gi\|77567877\|gb\|AAI074...	429.0	[0..1]	[606..1]
gi\|74007037, gi\|... - gi\|74007055\|ref\|XP_864875.1\| PREDICTED: similar to Melanoma-associated antigen D2 (MAGE-D2 antigen) ...	428.0	[0..1]	[606..1]

Back

Predicted Domain #1

Region A:
Residues: [1-169]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDTSESGAG LTRFQAEASE KDSSSMMQTL LTVTQNVEVP ETPKASKALE VSEDVKVSKA  60
   61 SGVSKATEVS KTPEAREAPA TQASSTTQLT DTQVLAAENK SLAADTKKQN ADPQAVTMPA 120
  121 TETKKVSHVA DTKVNTKAQE TEAAPSQAPA DEPEPESAAA QSQENQDTR

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [170-361]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKVKAKKARK VKHLDGEEDG SSDQSQASGT TGGRRVSKAL MASMARRASR GPIAFWARRA  60
   61 SRTRLAAWAR RALLSLRSPK ARRGKARRRA AKLQSSQEPE APPPRDVALL QGRANDLVKY 120
  121 LLAKDQTKIP IKRSDMLKDI IKEYTDVYPE IIERAGYSLE KVFGIQLKEI DKNDHLYILL 180
  181 STLEPTDAGI LG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [362-507]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTKDSPKLGL LMVLLSIIFM NGNRSSEAVI WEVLRKLGLR PGIHHSLFGD VKKLITDEFV  60
   61 KQKYLDYARV PNSNPPEYEF FWGLRSYYET SKMKVLKFAC KVQKKDPKEW AAQYREAMEA 120
  121 DLKAAAEAAA EAKARAEIRA RMGIGL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [508-606]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSENAAGPCN WDEADIGPWA KARIQAGAEA KAKAQESGSA STGASTSTNN SASASASTSG  60
   61 GFSAGASLTA TLTFGLFAGL GGAGASTSGS SGACGFSYK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits