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View Structure Prediction Details

Protein: MAGED2
Organism: Homo sapiens
Length: 606 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MAGED2.

Description E-value Query
Range
Subject
Range
gi|12659136 - gi|12659136|gb|AAK01204.1| mage-d2 [Mus musculus]
445.0 [0..1] [606..1]
MAGD2_PONPY - Melanoma-associated antigen D2 - Pongo pygmaeus (Orangutan)
MAGD2_PONAB - Melanoma-associated antigen D2 OS=Pongo abelii GN=MAGED2 PE=2 SV=1
436.0 [0..1] [606..1]
gi|4099969 - gi|4099969|gb|AAD00728.1| hepatocellular carcinoma associated protein [Homo sapiens]
434.0 [0..1] [606..1]
gi|109130890, gi... - gi|109130894|ref|XP_001091552.1| PREDICTED: melanoma antigen family D, 2 isoform 6 [Macaca mulatta],...
431.0 [0..1] [606..1]
gi|149031333, gi... - gi|78042585|ref|NP_536727.2| melanoma antigen family D, 2 [Rattus norvegicus], gi|77567877|gb|AAI074...
429.0 [0..1] [606..1]
gi|74007037, gi|... - gi|74007055|ref|XP_864875.1| PREDICTED: similar to Melanoma-associated antigen D2 (MAGE-D2 antigen) ...
428.0 [0..1] [606..1]

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Predicted Domain #1
Region A:
Residues: [1-169]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDTSESGAG LTRFQAEASE KDSSSMMQTL LTVTQNVEVP ETPKASKALE VSEDVKVSKA  60
   61 SGVSKATEVS KTPEAREAPA TQASSTTQLT DTQVLAAENK SLAADTKKQN ADPQAVTMPA 120
  121 TETKKVSHVA DTKVNTKAQE TEAAPSQAPA DEPEPESAAA QSQENQDTR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [170-361]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKVKAKKARK VKHLDGEEDG SSDQSQASGT TGGRRVSKAL MASMARRASR GPIAFWARRA  60
   61 SRTRLAAWAR RALLSLRSPK ARRGKARRRA AKLQSSQEPE APPPRDVALL QGRANDLVKY 120
  121 LLAKDQTKIP IKRSDMLKDI IKEYTDVYPE IIERAGYSLE KVFGIQLKEI DKNDHLYILL 180
  181 STLEPTDAGI LG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [362-507]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTKDSPKLGL LMVLLSIIFM NGNRSSEAVI WEVLRKLGLR PGIHHSLFGD VKKLITDEFV  60
   61 KQKYLDYARV PNSNPPEYEF FWGLRSYYET SKMKVLKFAC KVQKKDPKEW AAQYREAMEA 120
  121 DLKAAAEAAA EAKARAEIRA RMGIGL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.484 N/A N/A a.118.26 Description not found.
View Download 0.432 N/A N/A a.4.1 Homeodomain-like
View Download 0.412 N/A N/A a.74.1 Cyclin-like
View Download 0.387 N/A N/A a.118.1 ARM repeat
View Download 0.374 N/A N/A a.29.2 Bromodomain
View Download 0.374 N/A N/A a.29.2 Bromodomain
View Download 0.351 N/A N/A a.25.1 Ferritin-like
View Download 0.297 N/A N/A a.25.1 Ferritin-like
View Download 0.283 N/A N/A a.4.1 Homeodomain-like

Predicted Domain #4
Region A:
Residues: [508-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSENAAGPCN WDEADIGPWA KARIQAGAEA KAKAQESGSA STGASTSTNN SASASASTSG  60
   61 GFSAGASLTA TLTFGLFAGL GGAGASTSGS SGACGFSYK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.547 N/A N/A a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.547 N/A N/A a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.530 N/A N/A g.53.1 TAZ domain
View Download 0.530 N/A N/A g.53.1 TAZ domain
View Download 0.513 N/A N/A a.143.1 RNA polymerase omega subunit
View Download 0.512 N/A N/A a.143.1 RNA polymerase omega subunit
View Download 0.496 N/A N/A d.58.16 Poly(A) polymerase, C-terminal domain
View Download 0.471 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.471 N/A N/A a.24.17 Group V grass pollen allergen


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle