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View Structure Prediction Details

Protein: TAL1, TALDO1
Organism: Homo sapiens
Length: 337 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAL1, TALDO1.

Description E-value Query
Range		 Subject
Range
TALDO_RAT - Transaldolase OS=Rattus norvegicus GN=Taldo1 PE=1 SV=2
 0.0 [1..337] [1..337]
TALDO_MOUSE - Transaldolase OS=Mus musculus GN=Taldo1 PE=1 SV=2
 0.0 [1..337] [1..337]
TALDO_BOVIN - Transaldolase OS=Bos taurus GN=TALDO1 PE=2 SV=1
 0.0 [1..337] [1..337]
gi|53130752 - gi|53130752|emb|CAG31705.1| hypothetical protein [Gallus gallus]
 0.0 [1..337] [1..337]
gi|114635435, gi... - gi|114635437|ref|XP_001148375.1| PREDICTED: transaldolase 1 isoform 2 [Pan troglodytes], gi|11463543...
 0.0 [1..337] [1..337]
gi|48257056 - gi|48257056|gb|AAH18847.2| TALDO1 protein [Homo sapiens]
 0.0 [2..337] [1..336]
TALDO_CRIGR - Transaldolase OS=Cricetulus griseus GN=TALDO1 PE=2 SV=1
 0.0 [1..337] [1..337]
gi|57099501 - gi|57099501|ref|XP_533146.1| PREDICTED: similar to transaldolase 1 isoform 4 [Canis familiaris]
 0.0 [1..337] [1..337]
gi|55742472, gi|... - gi|55742472|ref|NP_955981.1| transaldolase 1 isoform 1 [Danio rerio], gi|38540850|gb|AAH61957.1| Tra...
gi|55742472 - ref|NP_955981.1| transaldolase 1 [Danio rerio]
 0.0 [1..337] [1..337]

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Predicted Domain #1
Region A:
Residues: [1-337] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSPVKRQR MESALDQLKQ FTTVVADTGD FHAIDEYKPQ DATTNPSLIL AAAQMPAYQE  60
   61 LVEEAIAYGR KLGGSQEDQI KNAIDKLFVL FGAEILKKIP GRVSTEVDAR LSFDKDAMVA 120
  121 RARRLIELYK EAGISKDRIL IKLSSTWEGI QAGKELEEQH GIHCNMTLLF SFAQAVACAE 180
  181 AGVTLISPFV GRILDWHVAN TDKKSYEPLE DPGVKSVTKI YNYYKKFSYK TIVMGASFRN 240
  241 TGEIKALAGC DFLTISPKLL GELLQDNAKL VPVLSAKAAQ ASDLEKIHLD EKSFRWLHNE 300
  301 DQMAVEKLSD GIRKFAADAV KLERMLTERM FNAENGK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 132.0
Match: 1f05A
Description: Transaldolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity, transferring aldehyde or ketonic groups 3.28746773527289 bayes_pls_golite062009
transaldolase activity 2.77878684721788 bayes_pls_golite062009
catalytic activity 2.67031204377352 bayes_pls_golite062009
fructose-bisphosphate aldolase activity 2.03916133349076 bayes_pls_golite062009
fructose binding 1.42916270771409 bayes_pls_golite062009
porphobilinogen synthase activity 0.658378297259497 bayes_pls_golite062009
binding 0.467753048702448 bayes_pls_golite062009
transferase activity 0.464721888799972 bayes_pls_golite062009
aldehyde-lyase activity 0.351872954170322 bayes_pls_golite062009
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