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View Structure Prediction Details

Protein: CBX1
Organism: Homo sapiens
Length: 185 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CBX1.

Description E-value Query
Range		 Subject
Range
gi|109067205 - gi|109067205|ref|XP_001095397.1| PREDICTED: similar to chromobox homolog 3 [Macaca mulatta]
 3.0E-56 [1..177] [270..440]
gi|109488886 - gi|109488886|ref|XP_340886.3| PREDICTED: similar to Chromobox protein homolog 1 (Heterochromatin pro...
 2.0E-50 [1..176] [565..740]
gi|114666540 - gi|114666540|ref|XP_523820.2| PREDICTED: similar to heterochromatin protein 1 beta [Pan troglodytes]
 6.0E-50 [1..176] [165..344]
gi|76645259 - gi|76645259|ref|XP_873631.1| PREDICTED: similar to Chromobox protein homolog 1 (Heterochromatin prot...
 5.0E-49 [1..176] [101..276]
gi|82913882, gi|... - gi|82913885|ref|XP_926464.1| PREDICTED: similar to Chromobox homolog 3 (HP1 gamma homolog, Drosophil...
 2.0E-43 [1..177] [11..181]
gi|7416937 - gi|7416937|gb|AAF62370.1|AF136630_1 heterochromatin-like protein 1 [Homo sapiens]
 2.0E-43 [1..177] [11..181]

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Predicted Domain #1
Region A:
Residues: [1-91] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKQNKKKV EEVLEEEEEE YVVEKVLDRR VVKGKVEYLL KWKGFSDEDN TWEPEENLDC  60
   61 PDLIAEFLQS QKTAHETDKS EGGKRKADSD S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.0
Match: 1ap0A
Description: STRUCTURE OF THE CHROMATIN BINDING (CHROMO) DOMAIN FROM MOUSE MODIFIER PROTEIN 1, NMR, 26 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.374364652893655 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [92-185] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDKGEESKPK KKKEESEKPR GFARGLEPER IIGATDSSGE LMFLMKWKNS DEADLVPAKE  60
   61 ANVKCPQVVI SFYEERLTWH SYPSEDDDKK DDKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.69897
Match: 1s4zA
Description: HP1 chromo shadow domain in complex with PXVXL motif of CAF-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.374364652893655 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle