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View Structure Prediction Details

Protein: ATXN10
Organism: Homo sapiens
Length: 475 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATXN10.

Description E-value Query
Range
Subject
Range
ATX10_MOUSE - Ataxin-10 OS=Mus musculus GN=Atxn10 PE=1 SV=2
0.0 [1..475] [1..475]
ATX10_RAT - Ataxin-10 OS=Rattus norvegicus GN=Atxn10 PE=1 SV=1
0.0 [1..475] [1..475]
ATX10_MACFA - Ataxin-10 OS=Macaca fascicularis GN=ATXN10 PE=2 SV=1
gi|109094541 - gi|109094541|ref|XP_001110207.1| PREDICTED: ataxin 10 [Macaca mulatta]
0.0 [1..475] [1..475]
ATX10_PONAB - Ataxin-10 OS=Pongo abelii GN=ATXN10 PE=2 SV=1
gi|55726464 - gi|55726464|emb|CAH90001.1| hypothetical protein [Pongo abelii]
0.0 [1..475] [1..476]
gi|73968907 - gi|73968907|ref|XP_531697.2| PREDICTED: similar to Ataxin-10 (Spinocerebellar ataxia type 10 protein...
0.0 [1..474] [1..474]
ATX10_BOVIN - Ataxin-10 OS=Bos taurus GN=ATXN10 PE=2 SV=1
0.0 [1..474] [1..474]
gi|114686960 - gi|114686960|ref|XP_525623.2| PREDICTED: hypothetical protein [Pan troglodytes]
0.0 [31..475] [6..450]

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Predicted Domain #1
Region A:
Residues: [1-475]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAPRPPPAR LSGVMVPAPI QDLEALRALT ALFKEQRNRE TAPRTIFQRV LDILKKSSHA  60
   61 VELACRDPSQ VENLASSLQL ITECFRCLRN ACIECSVNQN SIRNLDTIGV AVDLILLFRE 120
  121 LRVEQESLLT AFRCGLQFLG NIASRNEDSQ SIVWVHAFPE LFLSCLNHPD KKIVAYSSMI 180
  181 LFTSLNHERM KELEENLNIA IDVIDAYQKH PESEWPFLII TDLFLKSPEL VQAMFPKLNN 240
  241 QERVTLLDLM IAKITSDEPL TKDDIPVFLR HAELIASTFV DQCKTVLKLA SEEPPDDEEA 300
  301 LATIRLLDVL CEMTVNTELL GYLQVFPGLL ERVIDLLRVI HVAGKETTNI FSNCGCVRAE 360
  361 GDISNVANGF KSHLIRLIGN LCYKNKDNQD KVNELDGIPL ILDNCNISDS NPFLTQWVIY 420
  421 AIRNLTEDNS QNQDLIAKME EQGLADASLL KKVGFEVEKK GEKLILKSTR DTPKP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.57
Match: 1wa5B
Description: Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.88418925237229 bayes_pls_golite062009
protein binding 1.63424405980235 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle