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View Structure Prediction Details

Protein: gi|169158443, gi...
Organism: Homo sapiens
Length: 800 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|169158443, gi....

Description E-value Query
Range
Subject
Range
gi|114679033, gi... - gi|114679033|ref|XP_001174973.1| PREDICTED: leukocyte receptor cluster (LRC) member 8 isoform 5 [Pan...
0.0 [1..800] [1..800]
gi|109126046 - gi|109126046|ref|XP_001084592.1| PREDICTED: similar to leukocyte receptor cluster (LRC) member 8 [Ma...
0.0 [1..800] [1..751]
gi|76642537 - gi|76642537|ref|XP_604740.2| PREDICTED: similar to leukocyte receptor cluster (LRC) member 8 [Bos ta...
2.0E-95 [1..800] [1..797]
gi|73947557 - gi|73947557|ref|XP_533588.2| PREDICTED: similar to leukocyte receptor cluster (LRC) member 8 [Canis ...
1.0E-91 [1..747] [1..742]
LENG8_MOUSE - Leukocyte receptor cluster member 8 homolog OS=Mus musculus GN=Leng8 PE=1 SV=1
4.0E-91 [1..748] [1..749]

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Predicted Domain #1
Region A:
Residues: [1-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAANVGDQRS TDWSSQYSMV AGAGRENGME TPMHENPEWE KARQALASIS KSGAAGGSAK  60
   61 SSSNGPVASA QYVSQAEASA LQQQQYYQWY QQYNYAYPYS YYYPMSMYQS YGSPSQYGMA 120
  121 GSYGSATPQQ PSAPQHQGTL NQPPVPGMDE SMSYQAPPQQ LPSAQPPQPS NPPHGAHTLN 180
  181 SGPQPGTAPA TQHSQAGPAT GQAYGPHTYT EPAKP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [216-380]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKGQQLWNRM KPAPGTGGLK FNIQKRPFAV TTQSFGSNAE GQHSGFGPQP NPEKVQNHSG  60
   61 SSARGNLSGK PDDWPQDMKE YVERCFTACE SEEDKDRTEK LLKEVLQARL QDGSAYTIDW 120
  121 SREPLPGLTR EPVAESPKKK RWEAASSLHP PRGAGSATRG GGAPS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [381-574]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRGTPGAGGA GRARGNSFTK FGNRNVFMKD NSSSSSTDSR SRSSSRSPTR HFRRSDSHSD  60
   61 SDSSYSGNEC HPVGRRNPPP KGRGGRGAHM DRGRGRAQRG KRHDLAPTKR SRKKMAALEC 120
  121 EDPERELKKQ KRAARFQHGH SRRLRLEPLV LQMSSLESSG ADPDWQELQI VGTCPDITKH 180
  181 YLRLTCAPDP STVR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [575-800]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVAVLKKSLC MVKCHWKEKQ DYAFACEQMK SIRQDLTVQG IRTEFTVEVY ETHARIALEK  60
   61 GDHEEFNQCQ TQLKSLYAEN LPGNVGEFTA YRILYYIFTK NSGDITTELA YLTRELKADP 120
  121 CVAHALALRT AWALGNYHRF FRLYCHAPCM SGYLVDKFAD RERKVALKAM IKTFRPALPV 180
  181 SYLQAELAFE GEAACRAFLE PLGLAYTGPD NSSIDCRLSL AQLSAF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.15
Match: 1rz4A
Description: Crystal Structure of Human eIF3k
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.267627928716605 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle