| Protein: | ACO1 |
| Organism: | Homo sapiens |
| Length: | 889 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ACO1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..889] | [1..889] |
|
|
0.0 | [3..889] | [5..897] |
|
|
0.0 | [1..889] | [1..889] |
|
|
0.0 | [1..889] | [1..889] |
|
|
0.0 | [2..889] | [1..888] |
|
|
0.0 | [3..889] | [5..897] |
|
|
0.0 | [3..889] | [5..897] |
|
|
0.0 | [3..889] | [5..897] |
|
|
0.0 | [1..889] | [1..889] |
|
|
0.0 | [3..889] | [97..989] |
|
Region A: Residues: [1-889] |
1 11 21 31 41 51
| | | | | |
1 MSNPFAHLAE PLDPVQPGKK FFNLNKLEDS RYGRLPFSIR VLLEAAIRNC DEFLVKKQDI 60
61 ENILHWNVTQ HKNIEVPFKP ARVILQDFTG VPAVVDFAAM RDAVKKLGGD PEKINPVCPA 120
121 DLVIDHSIQV DFNRRADSLQ KNQDLEFERN RERFEFLKWG SQAFHNMRII PPGSGIIHQV 180
181 NLEYLARVVF DQDGYYYPDS LVGTDSHTTM IDGLGILGWG VGGIEAEAVM LGQPISMVLP 240
241 QVIGYRLMGK PHPLVTSTDI VLTITKHLRQ VGVVGKFVEF FGPGVAQLSI ADRATIANMC 300
301 PEYGATAAFF PVDEVSITYL VQTGRDEEKL KYIKKYLQAV GMFRDFNDPS QDPDFTQVVE 360
361 LDLKTVVPCC SGPKRPQDKV AVSDMKKDFE SCLGAKQGFK GFQVAPEHHN DHKTFIYDNT 420
421 EFTLAHGSVV IAAITSCTNT SNPSVMLGAG LLAKKAVDAG LNVMPYIKTS LSPGSGVVTY 480
481 YLQESGVMPY LSQLGFDVVG YGCMTCIGNS GPLPEPVVEA ITQGDLVAVG VLSGNRNFEG 540
541 RVHPNTRANY LASPPLVIAY AIAGTIRIDF EKEPLGVNAK GQQVFLKDIW PTRDEIQAVE 600
601 RQYVIPGMFK EVYQKIETVN ESWNALATPS DKLFFWNSKS TYIKSPPFFE NLTLDLQPPK 660
661 SIVDAYVLLN LGDSVTTDHI SPAGNIARNS PAARYLTNRG LTPREFNSYG SRRGNDAVMA 720
721 RGTFANIRLL NRFLNKQAPQ TIHLPSGEIL DVFDAAERYQ QAGLPLIVLA GKEYGAGSSR 780
781 DWAAKGPFLL GIKAVLAESY ERIHRSNLVG MGVIPLEYLP GENADALGLT GQERYTIIIP 840
841 ENLKPQMKVQ VKLDTGKTFQ AVMRFDTDVE LTYFLNGGIL NYMIRKMAK
|
| Detection Method: |  |
| Confidence: | 1000.0 |
| Match: | 2b3xA |
| Description: | Structure of an orthorhombic crystal form of human cytosolic aconitase (IRP1) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 3-isopropylmalate dehydratase activity | 11.6597692115322 | bayes_pls_golite062009 |
| aconitate hydratase activity | 5.86356477922338 | bayes_pls_golite062009 |
| structural constituent of ribosome | 2.93956285477489 | bayes_pls_golite062009 |
| catalytic activity | 2.4040324437254 | bayes_pls_golite062009 |
| nucleic acid binding | 2.25736437672211 | bayes_pls_golite062009 |
| carbon-oxygen lyase activity | 2.08349115784849 | bayes_pls_golite062009 |
| hydro-lyase activity | 2.04845291489052 | bayes_pls_golite062009 |
| lyase activity | 2.0080619912194 | bayes_pls_golite062009 |
| metal cluster binding | 1.70706327499066 | bayes_pls_golite062009 |
| iron-sulfur cluster binding | 1.70706327499066 | bayes_pls_golite062009 |
| binding | 1.67914740974449 | bayes_pls_golite062009 |
| DNA binding | 1.6436451615422 | bayes_pls_golite062009 |
| iron-responsive element binding | 1.1980380564483 | bayes_pls_golite062009 |
| iron ion binding | 1.12961684198784 | bayes_pls_golite062009 |
| 4 iron, 4 sulfur cluster binding | 1.11810757572823 | bayes_pls_golite062009 |
| mRNA binding | 1.0310744464034 | bayes_pls_golite062009 |
| structural molecule activity | 0.870913754566634 | bayes_pls_golite062009 |
| RNA binding | 0.42311333660604 | bayes_pls_golite062009 |
| transition metal ion binding | 0.342428816025605 | bayes_pls_golite062009 |
| protein binding | 0.232638130896339 | bayes_pls_golite062009 |
| cation binding | 0.0272064751959212 | bayes_pls_golite062009 |
| metal ion binding | 0.0272064751959212 | bayes_pls_golite062009 |
| ion binding | 0.0228992031160024 | bayes_pls_golite062009 |
