| Protein: | GTF2I |
| Organism: | Homo sapiens |
| Length: | 998 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GTF2I.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..998] | [1..998] |
|
|
0.0 | [1..998] | [1..999] |
|
|
0.0 | [1..998] | [1..999] |
|
|
0.0 | [1..998] | [1..978] |
|
|
0.0 | [1..998] | [1..998] |
|
Region A: Residues: [1-18] |
1 11 21 31 41 51
| | | | | |
1 MAQVAMSTLP VEDEESSE
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [19-81] |
1 11 21 31 41 51
| | | | | |
1 SRMVVTFLMS ALESMCKELA KSKAEVACIA VYETDVFVVG TERGRAFVNT RKDFQKDFVK 60
61 YCV
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.687 | 0.090 | transcription factor activity | d.88.1 | SRF-like |
| View | Download | 0.647 | 0.062 | transcription initiation from RNA polymerase II promoter | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.767 | 0.007 | transcription initiation from RNA polymerase II promoter | d.57.1 | DNA damage-inducible protein DinI |
| View | Download | 0.685 | N/A | N/A | d.88.1 | SRF-like |
| View | Download | 0.671 | N/A | N/A | d.88.1 | SRF-like |
|
Region A: Residues: [82-199] |
1 11 21 31 41 51
| | | | | |
1 EEEEKAAEMH KMKSTTQANR MSVDAVEIET LRKTVEDYFC FCYGKALGKS TVVPVPYEKM 60
61 LRDQSAVVVQ GLPEGVAFKH PENYDLATLK WILENKAGIS FIIKRPFLEP KKHVGGRV
|
| Detection Method: | |
| Confidence: | 38.69897 |
| Match: | 2d9bA |
| Description: | No description for 2d9bA was found. |
|
Region A: Residues: [200-300] |
1 11 21 31 41 51
| | | | | |
1 MVTDADRSIL SPGGSCGPIK VKTEPTEDSG ISLEMAAVTV KEESEDPDYY QYNIQAGPSE 60
61 TDDVDEKQPL SKPLQGSHHS SEGNEGTEME VPAEDSTQHV P
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [301-445] |
1 11 21 31 41 51
| | | | | |
1 SETSEDPEVE VTIEDDDYSP PSKRPKANEL PQPPVPEPAN AGKRKVREFN FEKWNARITD 60
61 LRKQVEELFE RKYAQAIKAK GPVTIPYPLF QSHVEDLYVE GLPEGIPFRR PSTYGIPRLE 120
121 RILLAKERIR FVIKKHELLN STRED
|
| Detection Method: | |
| Confidence: | 31.30103 |
| Match: | 2dn4A |
| Description: | No description for 2dn4A was found. |
|
Region A: Residues: [446-562] |
1 11 21 31 41 51
| | | | | |
1 LQLDKPASGV KEEWYARITK LRKMVDQLFC KKFAEALGST EAKAVPYQKF EAHPNDLYVE 60
61 GLPENIPFRS PSWYGIPRLE KIIQVGNRIK FVIKRPELLT HSTTEVTQPR TNTPVKE
|
| Detection Method: | |
| Confidence: | 6.42 |
| Match: | 2dzqA |
| Description: | No description for 2dzqA was found. |
|
Region A: Residues: [563-664] |
1 11 21 31 41 51
| | | | | |
1 DWNVRITKLR KQVEEIFNLK FAQALGLTEA VKVPYPVFES NPEFLYVEGL PEGIPFRSPT 60
61 WFGIPRLERI VRGSNKIKFV VKKPELVISY LPPGMASKIN TK
|
| Detection Method: | |
| Confidence: | 32.0 |
| Match: | 2dn5A |
| Description: | No description for 2dn5A was found. |
|
Region A: Residues: [665-714] |
1 11 21 31 41 51
| | | | | |
1 ALQSPKRPRS PGSNSKVPEI EVTVEGPNNN NPQTSAVRTP TQTNGSNVPF
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [715-828] |
1 11 21 31 41 51
| | | | | |
1 KPRGREFSFE AWNAKITDLK QKVENLFNEK CGEALGLKQA VKVPFALFES FPEDFYVEGL 60
61 PEGVPFRRPS TFGIPRLEKI LRNKAKIKFI IKKPEMFETA IKESTSSKSP PRKI
|
| Detection Method: | |
| Confidence: | 24.69897 |
| Match: | 1q60A |
| Description: | Solution Structure of RSGI RUH-004, a GTF2I domain in Mouse cDNA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.31986990828723 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 4.02258915980722 | bayes_pls_golite062009 |
| DNA binding | 4.01598187073916 | bayes_pls_golite062009 |
| nucleic acid binding | 3.9329721501879 | bayes_pls_golite062009 |
| transcription factor activity | 3.83217404681534 | bayes_pls_golite062009 |
| binding | 3.0325775548747 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.76277877142766 | bayes_pls_golite062009 |
| protein binding | 1.48651016577672 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.91960306002172 | bayes_pls_golite062009 |
| mitogen-activated protein kinase binding | 0.245342655759921 | bayes_pls_golite062009 |
|
Region A: Residues: [829-998] |
1 11 21 31 41 51
| | | | | |
1 NSSPNVNTTA SGVEDLNIIQ VTIPDDDNER LSKVEKARQL REQVNDLFSR KFGEAIGMGF 60
61 PVKVPYRKIT INPGCVVVDG MPPGVSFKAP SYLEISSMRR ILDSAEFIKF TVIRPFPGLV 120
121 INNQLVDQSE SEGPVIQESA EPSQLEVPAT EEIKETDGSS QIKQEPDPTW
|
| Detection Method: | |
| Confidence: | 42.0 |
| Match: | 2ejeA |
| Description: | No description for 2ejeA was found. |
