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View Structure Prediction Details

Protein: DAP3
Organism: Homo sapiens
Length: 398 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DAP3.

Description E-value Query
Range
Subject
Range
gi|61367201, gi|... - gi|61369407|gb|AAX43331.1| death associated protein 3 [synthetic construct], gi|61367201|gb|AAX42965...
0.0 [1..398] [1..398]
gi|55730281 - gi|55730281|emb|CAH91863.1| hypothetical protein [Pongo abelii]
gi|197098438 - gi|197098438|ref|NP_001127473.1| death associated protein 3 [Pongo abelii]
0.0 [1..398] [1..398]
gi|109017499 - gi|109017499|ref|XP_001113361.1| PREDICTED: similar to death-associated protein 3 [Macaca mulatta]
0.0 [1..398] [1..398]
gi|26328099 - gi|26328099|dbj|BAC27790.1| unnamed protein product [Mus musculus]
0.0 [2..398] [6..396]
gi|55249775, gi|... - gi|58865478|ref|NP_001011950.1| death associated protein 3 [Rattus norvegicus], gi|55249775|gb|AAH85...
0.0 [2..398] [1..391]
gi|76612491 - gi|76612491|ref|XP_580421.2| PREDICTED: similar to death-associated protein 3 [Bos taurus]
0.0 [1..398] [217..614]
gi|7430427, gi|6... - gi|7430427|pir||G01589 ionizing radiation resistance conferring protein - human, gi|603764|gb|AAA574...
0.0 [1..379] [1..379]

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Predicted Domain #1
Region A:
Residues: [1-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMLKGITRLI SRIHKLDPGR FLHMGTQARQ SIAAHLDNQV PVESPRAISR TNENDPAKHG  60
   61 DQHEGQHYNI SPQDLETVFP HGLPPRFVMQ VKT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [94-398]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSEACLMVRK PALELLHYLK NTSFAYPAIR YLLYGEKGTG KTLSLCHVIH FCAKQDWLIL  60
   61 HIPDAHLWVK NCRDLLQSSY NKQRFDQPLE ASTWLKNFKT TNERFLNQIK VQEKYVWNKR 120
  121 ESTEKGSPLG EVVEQGITRV RNATDAVGIV LKELKRQSSL GMFHLLVAVD GINALWGRTT 180
  181 LKREDKSPIA PEELALVHNL RKMMKNDWHG GAIVSALSQT GSLFKPRKAY LPQELLGKEG 240
  241 FDALDPFIPI LVSNYNPKEF ESCIQYYLEN NWLQHEKAPT EEGKKELLFL SNANPSLLER 300
  301 HCAYL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.12
Match: 2fnaA
Description: Crystal structure of (13814777) from SULFOLOBUS SOLFATARICUS at 2.00 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural constituent of ribosome 5.42139550243577 bayes_pls_golite062009
structural molecule activity 4.52418150951371 bayes_pls_golite062009
binding 2.15223415484989 bayes_pls_golite062009
protein binding 1.25232424749674 bayes_pls_golite062009
catalytic activity 0.942640875796745 bayes_pls_golite062009
motor activity 0.934327429601554 bayes_pls_golite062009
nucleic acid binding 0.88509145478589 bayes_pls_golite062009
cytoskeletal protein binding 0.482433345604081 bayes_pls_golite062009
microtubule motor activity 0.381564091226657 bayes_pls_golite062009
DNA binding 0.368768953337555 bayes_pls_golite062009
purine nucleotide binding 0.354154818458687 bayes_pls_golite062009
purine ribonucleotide binding 0.35085688811866 bayes_pls_golite062009
ribonucleotide binding 0.350844329183388 bayes_pls_golite062009
nucleotide binding 0.350227693353399 bayes_pls_golite062009
transcription regulator activity 0.181434122054025 bayes_pls_golite062009
translation regulator activity 0.165004576559811 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.144513585153713 bayes_pls_golite062009
RNA binding 0.10404338295854 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle