YRC Public Data Repository - Protein Structure Prediction

Protein:	VPS29
Organism:	Homo sapiens
Length:	182 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS29.

Description	E-value	Query Range	Subject Range
gi\|117644436 - gi\|117644436\|emb\|CAL37713.1\| hypothetical protein [synthetic construct] HGNC:14340\|MIM:6... - protein sorting 29 homolog (S. cerevisiae) gi\|12052754, gi\|... - gi\|49065362\|emb\|CAG38499.1\| VPS29 [Homo sapiens], gi\|12052754\|emb\|CAB66549.1\| hypothetical protein [...	2.0E-48	[1..182]	[1..182]
VPS29_DANRE - Vacuolar protein sorting-associated protein 29 OS=Danio rerio GN=vps29 PE=2 SV=1	2.0E-48	[1..181]	[1..181]
gi\|71042155, gi\|... - gi\|71042155\|pdb\|1Z2X\|B Chain B, Crystal Structure Of Mouse Vps29, gi\|71042154\|pdb\|1Z2X\|A Chain A, Cr...	4.0E-48	[1..181]	[11..191]
gi\|55729374 - gi\|55729374\|emb\|CAH91419.1\| hypothetical protein [Pongo abelii] VPS29_PONAB - Vacuolar protein sorting-associated protein 29 OS=Pongo abelii GN=VPS29 PE=2 SV=1	2.0E-47	[1..181]	[1..181]
gi\|110755558 - gi\|110755558\|ref\|XP_001121517.1\| PREDICTED: similar to vacuolar protein sorting 29 isoform 2 [Apis m...	2.0E-47	[2..181]	[11..190]
gi\|95103166, gi\|... - gi\|95103166\|gb\|ABF51524.1\| vacuolar protein sorting 29 isoform 2 [Bombyx mori], gi\|114053067\|ref\|NP_...	2.0E-47	[1..179]	[1..179]

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Predicted Domain #1

Region A:
Residues: [1-182]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVLVLGDLH IPHRCNSLPA KFKKLLVPGK IQHILCTGNL CTKESYDYLK TLAGDVHIVR  60
   61 GDFDENLNYP EQKVVTVGQF KIGLIHGHQV IPWGDMASLA LLQRQFDVDI LISGHTHKFE 120
  121 AFEHENKFYI NPGSATGAYN ALETNIIPSF VLMDIQASTV VTYVYQLIGD DVKVERIEYK 180
  181 KP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.0
Match:	1w24A
Description:	Crystal Structure Of human Vps29
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	2.15398287574737	bayes_pls_golite062009
protein transporter activity	1.31841400137462	bayes_pls_golite062009
transporter activity	1.24767072239634	bayes_pls_golite062009
phosphoric ester hydrolase activity	1.23826159413064	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.13357344565764	bayes_pls_golite062009
protein serine/threonine phosphatase activity	1.09206313505563	bayes_pls_golite062009
phosphatase activity	1.08894272596476	bayes_pls_golite062009
binding	1.0086165150304	bayes_pls_golite062009
substrate-specific transporter activity	0.783004917746429	bayes_pls_golite062009
phosphoprotein phosphatase activity	0.521298686118866	bayes_pls_golite062009
protein binding	0.306836734324834	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: