YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|48145659, gi|...
Organism: Homo sapiens
Length: 464 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|48145659, gi|....

Description E-value Query
Range
Subject
Range
gi|61369343 - gi|61369343|gb|AAX43320.1| heterogeneous nuclear ribonucleoprotein K [synthetic construct]
9.0E-88 [1..464] [1..464]
HNRPK_BOVIN - Heterogeneous nuclear ribonucleoprotein K OS=Bos taurus GN=HNRNPK PE=2 SV=1
1.0E-87 [1..464] [1..464]
gi|74177637 - gi|74177637|dbj|BAE38921.1| unnamed protein product [Mus musculus]
2.0E-87 [1..464] [1..464]
gi|1083569 - gi|1083569|pir||A54143 kappa-B motif-binding phosphoprotein - mouse
2.0E-87 [1..464] [1..464]
gi|460789 - gi|460789|emb|CAA51267.1| transformation upregulated nuclear protein [Homo sapiens]
3.0E-87 [1..464] [1..464]
gi|473912 - gi|473912|gb|AAA21731.1| phosphoprotein
1.0E-86 [1..464] [1..464]
HNRPK_RABIT - Heterogeneous nuclear ribonucleoprotein K OS=Oryctolagus cuniculus GN=HNRNPK PE=2 SV=1
4.0E-86 [1..457] [1..457]

Back

Predicted Domain #1
Region A:
Residues: [1-99]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METEQPEETF PNTETNGEFG KRPAEDMEEE QAFKRSRNTD EMVELRILLQ SKNAGAVIGK  60
   61 GGKNIKALRT DYNASVSVPD SSGPERILSI SADIETIGE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.522879
Match: 2annA
Description: No description for 2annA was found.

Predicted Domain #2
Region A:
Residues: [100-384]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILKKIIPTLE EGLQLPSPTA TSQLPLESDA VECLNYQHYK GSDFDCELRL LIHQSLAGGI  60
   61 IGVKGAKIKE LRENTQTTIK LFQECCPHST DRVVLIGGKP DRVVECIKII LDLISESPIK 120
  121 GRAQPYDPNF YDETYDYGGF TMMFDDRRGR PVGFPMRGRG GFDRMPPGRG GRPMPPSRRD 180
  181 YDDMSPRRGP PPPPPGRGGR GGSRARNLPL PPPPPPRGGD LMAYDRRGRP GDRYDGMVGF 240
  241 SADETWDSAI DTWSPSEWQM AYEPQGGSGY DYSYAGGRGS YGDLG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.99
Match: 1j4wA
Description: Far upstream binding element, FBP, KH3 and KH4 domains
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.35205331138538 bayes_pls_golite062009
mRNA binding 4.67566555881601 bayes_pls_golite062009
nucleic acid binding 3.42924343218473 bayes_pls_golite062009
binding 3.31439627344982 bayes_pls_golite062009
2.82262844310386 bayes_pls_golite062009
poly-pyrimidine tract binding 1.75736205236351 bayes_pls_golite062009
transcription regulator activity 1.42352554448586 bayes_pls_golite062009
DNA binding 1.19165437089346 bayes_pls_golite062009
protein binding 1.09698608157472 bayes_pls_golite062009
single-stranded RNA binding 0.795008427109843 bayes_pls_golite062009
transcription factor activity 0.392247064645943 bayes_pls_golite062009
structure-specific DNA binding 0.158813798830905 bayes_pls_golite062009
catalytic activity 0.1435046019283 bayes_pls_golite062009
mRNA 3'-UTR binding 0.137373295657998 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [385-464]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPIITTQVTI PKDLAGSIIG KGGQRIKQIR HESGASIKID EPLEGSEDRI ITITGTQDQI  60
   61 QNAQYLLQNS VKQYADVEGF 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.69897
Match: 1j5kA
Description: HnRNP K, KH3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.76415077523249 bayes_pls_golite062009
mRNA binding 5.07455187994216 bayes_pls_golite062009
nucleic acid binding 3.68444148122352 bayes_pls_golite062009
binding 3.45962790790935 bayes_pls_golite062009
2.87067043110488 bayes_pls_golite062009
poly-pyrimidine tract binding 2.05765562493656 bayes_pls_golite062009
transcription regulator activity 1.43703138180882 bayes_pls_golite062009
DNA binding 1.20852534725468 bayes_pls_golite062009
protein binding 1.16541072642796 bayes_pls_golite062009
single-stranded RNA binding 0.981003625136521 bayes_pls_golite062009
mRNA 3'-UTR binding 0.489176583045793 bayes_pls_golite062009
transcription factor activity 0.386248501195543 bayes_pls_golite062009
structure-specific DNA binding 0.32222928997178 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009
single-stranded DNA binding 0.1069917291606 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle