YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: KHDRBS1
Organism: Homo sapiens
Length: 443 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KHDRBS1.

Description E-value Query
Range
Subject
Range
KHDR1_RAT - KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Rattus norvegicus GN=...
0.0 [1..443] [1..443]
KHDR1_MOUSE - KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Mus musculus GN=Khdrb...
0.0 [1..443] [1..443]
gi|67971968 - gi|67971968|dbj|BAE02326.1| unnamed protein product [Macaca fascicularis]
0.0 [1..443] [1..443]
gi|88954299, gi|... - gi|88954299|gb|AAI14076.1| KH domain containing, RNA binding, signal transduction associated 1 [Bos ...
0.0 [1..443] [1..443]
gi|21749696 - gi|21749696|dbj|BAC03643.1| unnamed protein product [Homo sapiens]
0.0 [1..443] [1..418]
gi|114555300 - gi|114555300|ref|XP_513273.2| PREDICTED: similar to p62 [Pan troglodytes]
0.0 [1..443] [205..641]
gi|73950011 - gi|73950011|ref|XP_864860.1| PREDICTED: similar to KH domain containing, RNA binding, signal transdu...
0.0 [21..443] [1..405]

Back

Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQRRDDPAAR MSRSSGRSGS MDPSGAHPSV RQTPSRQPPL PHRSRGGGGG SRGGARASPA  60
   61 TQPPPLLPPS ATGPDATVGG PAPTPL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [87-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPPSATASVK MEPENKYLPE LMAEKDSLDP SFTHAMQLLT AEIEKIQKG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [136-297]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSKKDDEENY LDLFSHKNMK LKERVLIPVK QYPKFNFVGK ILGPQGNTIK RLQEETGAKI  60
   61 SVLGKGSMRD KAKEEELRKG GDPKYAHLNM DLHVFIEVFG PPCEAYALMA HAMEEVKKFL 120
  121 VPDMMDDICQ EQFLELSYLN GVPEPSRGRG VPVRGRGAAP PP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.69897
Match: 2bl5A
Description: Solution structure of the KH-QUA2 region of the Xenopus STAR-GSG Quaking protein.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 5.18414740305744 bayes_pls_golite062009
nucleic acid binding 4.48152042822746 bayes_pls_golite062009
mRNA binding 3.82977088614136 bayes_pls_golite062009
binding 3.45962790790935 bayes_pls_golite062009
transcription regulator activity 2.54125642939085 bayes_pls_golite062009
DNA binding 2.21410605855315 bayes_pls_golite062009
transcription repressor activity 2.05847856402521 bayes_pls_golite062009
transcription factor activity 1.22994056525688 bayes_pls_golite062009
protein binding 1.16541072642796 bayes_pls_golite062009
0.800987648548054 bayes_pls_golite062009
signal transducer activity 0.770583526648683 bayes_pls_golite062009
molecular transducer activity 0.770583526648683 bayes_pls_golite062009
mRNA 3'-UTR binding 0.489176583045793 bayes_pls_golite062009
transcription activator activity 0.404927707462702 bayes_pls_golite062009
poly-pyrimidine tract binding 0.30467150200016 bayes_pls_golite062009
transcription factor binding 0.274119533759015 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009
sequence-specific DNA binding 0.0321875054165348 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [298-443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPVPRGRGVG PPRGALVRGT PVRGAITRGA TVTRGVPPPP TVRGAPAPRA RTAGIQRIPL  60
   61 PPPPAPETYE EYGYDDTYAE QSYEGYEGYY SQSQGDSEYY DYGHGEVQDS YEAYGQDDWN 120
  121 GTRPSLKAPP ARPVKGAYRE HPYGRY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle