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View Structure Prediction Details

Protein: gi|14141159, gi|...
Organism: Homo sapiens
Length: 331 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|14141159, gi|....

Description E-value Query
Range
Subject
Range
gi|73976797 - gi|73976797|ref|XP_857696.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
2.0E-47 [3..330] [86..449]
gi|76689285 - gi|76689285|ref|XP_881509.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 2 ...
4.0E-47 [3..330] [86..453]
gi|55959639, gi|... - gi|66267552|gb|AAH94755.1| PABPC4 protein [Homo sapiens], gi|55962217|emb|CAI12298.1| poly(A) bindin...
gi|114555673 - gi|114555673|ref|XP_001170937.1| PREDICTED: poly A binding protein, cytoplasmic 4 isoform 1 [Pan tro...
6.0E-47 [3..330] [86..449]
gi|55959640, gi|... - gi|55962218|emb|CAI12299.1| poly(A) binding protein, cytoplasmic 4 (inducible form) [Homo sapiens], ...
6.0E-47 [3..330] [86..449]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDWVMKHNGP NDASDGTVRL RGLPFGCSKE EIVQFFQGLE IVPNGITLTM DYQGRSTGEA  60
   61 FVQFASKEIA ENALGKHKER IGHRYIEIFR SSRSEIKGFY DPP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.221849
Match: 1wg5A
Description: Solution structure of the first RRM domain in heterogeneous nuclear ribonucleoprotein H
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [104-331]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRLLGQRPGP YDRPIGGRGG YYGAGRGSYG GFDDYGGYNN YGYGNDGFDD RMRDGRGMGG  60
   61 HGYGGAGDAS SGFHGGHFVH MRGLPFRATE NDIANFFSPL NPIRVHIDIG ADGRATGEAD 120
  121 VEFVTHEDAV AAMSKDKNNM QHRYIELFLN STPGGGSGMG GSGMGGYGRD GMDNQGGYGS 180
  181 VGRMGMGNNY SGGYGTPDGL GGYGRGGGGS GGYYGQGGMS GGGWRGMY

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.06
Match: 1l3kA
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.787118623292657 bayes_pls_golite062009
nucleic acid binding 0.0269483316710413 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle