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View Structure Prediction Details

Protein: SKP2
Organism: Homo sapiens
Length: 424 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SKP2.

Description E-value Query
Range
Subject
Range
gi|113547417, gi... - gi|115450691|ref|NP_001048946.1| Os03g0145000 [Oryza sativa (japonica cultivar-group)], gi|113547417...
3.0E-64 [10..423] [110..591]

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Predicted Domain #1
Region A:
Residues: [1-333]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHRKHLQEIP DLSSNVATSF TWGWDSSKTS ELLSGMGVSA LEKEEPDSEN IPQELLSNLG  60
   61 HPESPPRKRL KSKGSDKDFV IVRRPKLNRE NFPGVSWDSL PDELLLGIFS CLCLPELLKV 120
  121 SGVCKRWYRL ASDESLWQTL DLTGKNLHPD VTGRLLSQGV IAFRCPRSFM DQPLAEHFSP 180
  181 FRVQHMDLSN SVIEVSTLHG ILSQCSKLQN LSLEGLRLSD PIVNTLAKNS NLVRLNLSGC 240
  241 SGFSEFALQT LLSSCSRLDE LNLSWCFDFT EKHVQVAVAH VSETITQLNL SGYRKNLQKS 300
  301 DLSTLVRRCP NLVHLDLSDS VMLKNDCFQE FFQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 2omxA
Description: No description for 2omxA was found.

Predicted functions:

Term Confidence Notes
protein binding 1.69661396118522 bayes_pls_golite062009
binding 1.23313855731605 bayes_pls_golite062009
receptor activity 0.823142813332745 bayes_pls_golite062009
nucleic acid binding 0.710443686489925 bayes_pls_golite062009
transmembrane receptor activity 0.569410390698942 bayes_pls_golite062009
signal transducer activity 0.405945668463821 bayes_pls_golite062009
molecular transducer activity 0.405945668463821 bayes_pls_golite062009
protein kinase activity 0.0574120480524489 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [334-424]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNYLQHLSLS RCYDIIPETL LELGEIPTLK TLQVFGIVPD GTLQLLKEAL PHLQINCSHF  60
   61 TTIARPTIGN KKNQEIWGIK CRLTLQKPSC L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.09691
Match: 1fqvA
Description: Skp2; Cyclin A/CDK2-associated p19, Skp2
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle