YRC Public Data Repository - Protein Structure Prediction

Protein:	PIP
Organism:	Homo sapiens
Length:	146 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PIP.

Description	E-value	Query Range	Subject Range
gi\|76616535 - gi\|76616535\|ref\|XP_591612.2\| PREDICTED: similar to Alpha-2-macroglobulin precursor (Alpha-2-M) isofo...	2.0E-40	[4..146]	[759..910]
A2MG_RAT - (P06238) Alpha-2-macroglobulin precursor (Alpha-2-M)	1.0E-39	[2..146]	[750..904]
gi\|758425 - gi\|758425\|gb\|AAB60608.1\| complement component C3 gi\|1580935 - gi\|1580935\|prf\|\|2116268A complement C3	4.0E-39	[2..146]	[713..874]
gi\|28274695, gi\|... - gi\|28274695\|ref\|NP_783327.1\| alpha-2-macroglobulin [Mus musculus], gi\|27966961\|gb\|AAO25741.1\| alpha-...	4.0E-39	[2..146]	[751..905]

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Predicted Domain #1

Region A:
Residues: [1-146]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLLQLLFRA SPATLLLVLC LQLGANKAQD NTRKIIIKNF DIPKSVRPND EVTAVLAVQT  60
   61 ELKECMVVKT YLISSIPLQG AFNYKYTACL CDDNPKTFYW DFYTNRTVQI AAVVDVIREL 120
  121 GICPDDAAVI PIKNNRFYTI EILKVE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.0
Match:	2icnB
Description:	No description for 2icnB was found.

Predicted functions:

Term	Confidence	Notes
binding	0.375578823918741	bayes_pls_golite062009
protein binding	0.0393948794857494	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: