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View Structure Prediction Details

Protein: gi|4938296, gi|2...
Organism: Homo sapiens
Length: 290 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|4938296, gi|2....

Description E-value Query
Range
Subject
Range
gi|213417799, gi... - gi|74191742|dbj|BAE32830.1| unnamed protein product [Mus musculus], gi|74183099|dbj|BAE22515.1| unna...
5.0E-50 [1..290] [1..296]
gi|58865494, gi|... - gi|58865494|ref|NP_001011958.1| RNA binding protein, autoantigenic (hnRNP-associated with lethal yel...
2.0E-49 [1..290] [1..295]
gi|62460386, gi|... - gi|62460386|ref|NP_001014847.1| RNA binding protein (autoantigenic, hnRNP-associated with lethal yel...
2.0E-48 [1..290] [1..283]
gi|3334899 - gi|3334899|gb|AAC28898.1| autoantigen p542 [Homo sapiens]
3.0E-48 [1..290] [1..291]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLKLQASNV TNKNDPKSIN SRVFIGNLNT ALVKKSDVET IFSKYGRVAG CSVHKGYAFV  60
   61 QYSNERHARA AVLGENGRVL AGQTLDINMA GEPKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.30103
Match: 1wf1A
Description: Solution structure of RRM domain in RNA-binding protein NP_057951
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.96087565414382 bayes_pls_golite062009
binding 2.29041217255208 bayes_pls_golite062009
nucleic acid binding 1.91189490017911 bayes_pls_golite062009
mRNA binding 1.52245536665132 bayes_pls_golite062009
protein binding 0.0101134374085809 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [96-290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRPKGLKRAA SAIYRLFDYR GRLSPVPVPR AVPVKRPRVT VPLVRRVKTN VPVKLFARST  60
   61 AVTTSSAKIK LKSSELQAIK TELTQIKSNI DALLSRLEQI AAEQKANPDG KKKGDGGGAG 120
  121 GGGGGGGSGG GGSGGGGGGG SSRPPAPQEN TTSEAGLPQG EARTRDDGDE EGLLTHSEEE 180
  181 LEHSQDTDAD DGALQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle