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View Structure Prediction Details

Protein: SSZ1
Organism: Saccharomyces cerevisiae
Length: 538 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SSZ1.

Description E-value Query
Range		 Subject
Range
gi|27802643 - gi|27802643|gb|AAO21473.1| hsp70 family member [Locusta migratoria]
 0.0 [3..538] [5..504]
gi|45544523 - gi|45544523|dbj|BAD12572.1| heat shock protein [Numida meleagris]
gi|50759965 - ref|XP_429266.1| PREDICTED: hypothetical protein XP_429266 [Gallus gallus]
gi|118722053, gi... - gi|118722053|dbj|BAF38392.1| heat shock protein 70kDa [Coturnix japonica], gi|118197131|dbj|BAF37041...
 0.0 [1..538] [1..503]
HSP70_ONCTS - Heat shock 70 kDa protein OS=Oncorhynchus tshawytscha GN=hsp70 PE=2 SV=1
 0.0 [1..538] [1..505]
gi|42542422 - gi|42542422|gb|AAH66191.1| Heat shock protein 8 [Mus musculus]
 0.0 [1..538] [1..503]
HSP7C_RAT - Heat shock cognate 71 kDa protein OS=Rattus norvegicus GN=Hspa8 PE=1 SV=1
HSP7C_MOUSE - Heat shock cognate 71 kDa protein OS=Mus musculus GN=Hspa8 PE=1 SV=1
gi|148234651, gi... - gi|148234651|ref|NP_001091238.1| hypothetical protein LOC100037033 [Xenopus laevis], gi|120577579|gb...
 0.0 [1..538] [1..503]
gi|123980484, gi... - gi|123995299|gb|ABM85251.1| heat shock 70kDa protein 8 [synthetic construct], gi|123980484|gb|ABM820...
HSP7C_HORSE - Heat shock cognate 71 kDa protein OS=Equus caballus GN=HSPA8 PE=2 SV=1
gi|197097502 - gi|197097502|ref|NP_001125783.1| heat shock 70kDa protein 8 [Pongo abelii]
gi|109109056 - gi|109109056|ref|XP_001108049.1| PREDICTED: heat shock 70kDa protein 8 [Macaca mulatta]
gi|55729181 - gi|55729181|emb|CAH91327.1| hypothetical protein [Pongo abelii]
gi|183636984 - gi|183636984|gb|ACC64541.1| heat shock protein 8 (predicted) [Rhinolophus ferrumequinum]
HSP7C_SAGOE - Heat shock cognate 71 kDa protein OS=Saguinus oedipus GN=HSPA8 PE=2 SV=1
gi|57085907 - gi|57085907|ref|XP_536543.1| PREDICTED: similar to Heat shock cognate 71 kDa protein (Heat shock 70 ...
tr|M3VW17|M3VW17... - Uncharacterized protein OS=Felis catus GN=HSPA8 PE=3 SV=1
HSPA8 - heat shock 70kDa protein 8
gi|114640901 - gi|114640901|ref|XP_508830.2| PREDICTED: heat shock 70kDa protein 8 [Pan troglodytes]
 0.0 [1..538] [1..503]
gi|7861932, gi|1... - gi|7861932|gb|AAF70445.1| Hsp70 [Danio rerio], gi|18858871|ref|NP_571472.1| heat shock cognate 70-kd...
 0.0 [1..538] [1..505]
HSP7C_CHICK - Heat shock cognate 71 kDa protein OS=Gallus gallus GN=HSPA8 PE=1 SV=1
 0.0 [1..538] [1..503]
gi|16041102 - gi|16041102|dbj|BAB69718.1| hypothetical protein [Macaca fascicularis]
 0.0 [1..538] [1..503]

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Predicted Domain #1
Region A:
Residues: [1-388] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSPVIGITF GNTSSSIAYI NPKNDVDVIA NPDGERAIPS ALSYVGEDEY HGGQALQQLI  60
   61 RNPKNTIINF RDFIGLPFDK CDVSKCANGA PAVEVDGKVG FVISRGEGKE EKLTVDEVVS 120
  121 RHLNRLKLAA EDYIGSAVKE AVLTVPTNFS EEQKTALKAS AAKIGLQIVQ FINEPSAALL 180
  181 AHAEQFPFEK DVNVVVADFG GIRSDAAVIA VRNGIFTILA TAHDLSLGGD NLDTELVEYF 240
  241 ASEFQKKYQA NPRKNARSLA KLKANSSITK KTLSNATSAT ISIDSLADGF DYHASINRMR 300
  301 YELVANKVFA QFSSFVDSVI AKAELDPLDI DAVLLTGGVS FTPKLTTNLE YTLPESVEIL 360
  361 GPQNKNASNN PNELAASGAA LQARLISD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 176.0
Match: 1hpm__
Description: Heat shock protein 70kDa, ATPase fragment
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
unfolded protein binding 2.80511977200055 bayes_pls_golite062009
structural constituent of cytoskeleton 2.46121037473545 bayes_pls_golite062009
structural molecule activity 2.37892721989886 bayes_pls_golite062009
cytoskeletal protein binding 2.20983242331685 bayes_pls_golite062009
binding 2.11855816699924 bayes_pls_golite062009
transcription regulator activity 1.68670098354938 bayes_pls_golite062009
nucleic acid binding 1.43834016708999 bayes_pls_golite062009
DNA binding 1.36804228074586 bayes_pls_golite062009
actin binding 1.03829083423378 bayes_pls_golite062009
protein binding 0.956664772028256 bayes_pls_golite062009
hydrolase activity 0.921698825968978 bayes_pls_golite062009
carbohydrate kinase activity 0.907850179362196 bayes_pls_golite062009
transcription factor activity 0.783439770973386 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.712286564783673 bayes_pls_golite062009
kinase activity 0.641356183582417 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.63007037584851 bayes_pls_golite062009
hexokinase activity 0.615559272345961 bayes_pls_golite062009
pyrophosphatase activity 0.537281794852105 bayes_pls_golite062009
myosin binding 0.31501932970343 bayes_pls_golite062009
catalytic activity 0.296484721581333 bayes_pls_golite062009
protease binding 0.168989471696885 bayes_pls_golite062009
chaperone binding 0.00111313452804307 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [389-538] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDADELAEAL QPVIVNTPHL KKPIGLIGAK GEFHPVLLAE TSFPVQKKLT LKQAKGDFLI  60
   61 GVYEGDHHIE EKTLEPIPKE ENAEEDDESE WSDDEPEVVR EKLYTLGTKL MELGIKNANG 120
  121 VEIIFNINKD GALRVTARDL KTGNAVKGEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.69897
Match: 1ckrA_
Description: DnaK
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle