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View Structure Prediction Details

Protein: MPS3
Organism: Saccharomyces cerevisiae
Length: 682 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MPS3.

Description E-value Query
Range
Subject
Range
MPS3 - Nuclear envelope protein required for SPB duplication and nuclear fusion; localizes to the SPB half ...
MPS3_YEAST - Spindle pole body assembly component MPS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
YJL019W_W303, Mps3 - MPS3 ORF Verified Nuclear envelope protein; required for SPB insertion, initiation of SPB duplicatio...
0.0 [1..682] [1..682]
gi|44986342 - gi|44986342|gb|AAS54802.1| AGR312Wp [Ashbya gossypii ATCC 10895]
gi|44986342, gi|... - gi|45201408|ref|NP_986978.1| AGR312Wp [Ashbya gossypii ATCC 10895], gi|44986342|gb|AAS54802.1| AGR31...
0.0 [16..681] [6..615]

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Predicted Domain #1
Region A:
Residues: [1-180]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNSNEHRRE EAGAANEQMP YNKAVKSAYA DVLKDKMNRE QEISLRAIKK GIYTDGGETD  60
   61 NYDMDKENDS AYEMFKKNLD FPLDQHNDDD DDDPYIEDNG QETDGYSDED YTDEADKSFI 120
  121 EDSDSDSYDL ESNSDFEENL ESSGEAKKLK WRTYIFYGGL FFVFYFFGSF LMTTVKNNDL 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [181-332]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESHSSGATSS PGKSFSNLQK QVNHLYSELS KRDEKHSSEL DKTVKIIVSQ FEKNIKRLLP  60
   61 SNLVNFENDI NSLTKQVETI STSMSELQRR NHKFTVENVT QWQDQLVKQL DTHLPQEIPV 120
  121 VINNSSSLLI IPELHNYLSA LISDVIESPG IG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 2.13881908809926 bayes_pls_golite062009
protein binding 1.02790379418228 bayes_pls_golite062009
receptor activity 0.850578317637287 bayes_pls_golite062009
transmembrane receptor activity 0.718598814428587 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.081069822885576 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [333-575]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAGSAESRWE YDLNRYVKEI LSNELQYIDK DYFIQEMNRR LQSNKQEIWE EITNRLETQQ  60
   61 QQQQQQVQQD YSNVPQQYSS ILMKRLIHQI YNSNQHQWED DLDFATYVQG TKLLNHLTSP 120
  121 TWRQGSGVQP IELLTDSKQS SSTYWQCENE PGCSWAIRFK TPLYLTKISY MHGRFTNNLH 180
  181 IMNSAPRLIS LYVKLSQTKE IKALQTLANQ YGFGQHHKRD RNYIKIAKFE YRLTDSRIRQ 240
  241 QMY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [576-682]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPPWFIQLKP LVRSIVFQVD ENYGNKKFIS LRKFIINGVT PQDLQIIENN EFPVLLGDTP  60
   61 EYGVTQNTDE GKRKVLLSKP PYASSSTSTK FHPASNVPSF GQDELDQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle