YRC Public Data Repository - Protein Structure Prediction

Protein:	PMT2
Organism:	Saccharomyces cerevisiae
Length:	759 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PMT2.

Description	E-value	Query Range	Subject Range
PMT2_YEAST - Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Saccharomyces cerevisiae (strain ATCC 2... PMT2 - Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to prote... gi\|190406671 - gi\|190406671\|gb\|EDV09938.1\| dolichyl-phosphate-mannose-protein mannosyltransferase 2 [Saccharomyces ...	0.0	[1..759]	[1..759]
gi\|32415215, gi\|... - gi\|9368945\|emb\|CAB99175.1\| probable dolichyl-phosphate-mannose--protein mannosyltransferase [Neurosp... gi\|85079003 - gi\|85079003\|ref\|XP_956270.1\| probable dolichyl-phosphate-mannose--protein mannosyltransferase [MIPS]...	0.0	[1..755]	[1..748]
gi\|14625800 - gi\|14625800\|gb\|AAK71510.1\| dolichyl-phosphate-mannose:protein mannosyltransferase [Emericella nidula... gi\|49095562, gi\|... - gi\|67537870\|ref\|XP_662709.1\| hypothetical protein AN5105.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	0.0	[12..755]	[7..740]
gi\|15011522 - gi\|15011522\|gb\|AAK77607.1\|AF396953_1 protein O-mannosyl transferase [Aspergillus awamori]	0.0	[8..755]	[3..741]
gi\|46109306, gi\|... - gi\|46109306\|ref\|XP_381711.1\| hypothetical protein FG01535.1 [Gibberella zeae PH-1], gi\|42545318\|gb\|E...	0.0	[11..755]	[7..741]
orf19.6812, orf1... - PMT2 CGDID:CAL0005653 Assembly 19, Contig19-10254 (190330, 188021) CDS, reverse complemented, transl... PMT2_CANAL - Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Candida albicans (strain SC5314 / ATCC ...	0.0	[6..757]	[2..767]
gi\|44981766 - gi\|44981766\|gb\|AAS51516.1\| ACR290Wp [Ashbya gossypii ATCC 10895] gi\|44981766, gi\|... - gi\|45185976\|ref\|NP_983692.1\| ACR290Wp [Ashbya gossypii ATCC 10895], gi\|44981766\|gb\|AAS51516.1\| ACR29...	0.0	[5..754]	[14..755]

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Predicted Domain #1

Region A:
Residues: [1-110]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSSSTGYS KNNAAHIKQE NTLRQRESSS ISVSEELSSA DERDAEDFSK EKPAAQSSLL  60
   61 RLESVVMPVI FTALALFTRM YKIGINNHVV WDEAHFGKFG SYYLRHEFYH

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [111-311]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVHPPLGKML VGLSGYLAGY NGSWDFPSGE IYPDYLDYVK MRLFNASFSA LCVPLAYFTA  60
   61 KAIGFSLPTV WLMTVLVLFE NSYSTLGRFI LLDSMLLFFT VASFFSFVMF HNQRSKPFSR 120
  121 KWWKWLLITG ISLGCTISVK MVGLFIITMV GIYTVIDLWT FLADKSMSWK TYINHWLARI 180
  181 FGLIIVPFCI FLLCFKIHFD L

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [312-407]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSHSGTGDAN MPSLFQARLV GSDVGQGPRD IALGSSVVSI KNQALGGSLL HSHIQTYPDG  60
   61 SNQQQVTCYG YKDANNEWFF NRERGLPSWS ENETDI

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	13.39794
Match:	PF02815.7
Description:	No description for PF02815.7 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
dolichyl-phosphate-mannose-protein mannosyltransferase activity	7.33543412640964	bayes_pls_golite062009
mannosyltransferase activity	6.32966341675541	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	2.60661923349025	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.57555885876017	bayes_pls_golite062009
receptor activity	1.99332745476324	bayes_pls_golite062009
binding	1.86366637427031	bayes_pls_golite062009
molecular transducer activity	1.71523634580131	bayes_pls_golite062009
signal transducer activity	1.71523634580131	bayes_pls_golite062009
cation channel activity	1.66500687404195	bayes_pls_golite062009
ion channel activity	1.61859406934521	bayes_pls_golite062009
substrate-specific channel activity	1.57127083095499	bayes_pls_golite062009
passive transmembrane transporter activity	1.55374970486978	bayes_pls_golite062009
channel activity	1.55374970486978	bayes_pls_golite062009
inositol-1,4,5-trisphosphate receptor activity	1.28298370923705	bayes_pls_golite062009
transferase activity	0.981084601370981	bayes_pls_golite062009
calcium channel activity	0.85901349040585	bayes_pls_golite062009
catalytic activity	0.659936859803906	bayes_pls_golite062009
calcium-release channel activity	0.65133561512386	bayes_pls_golite062009
gated channel activity	0.53737429019655	bayes_pls_golite062009
ligand-gated ion channel activity	0.52162184692236	bayes_pls_golite062009
ligand-gated channel activity	0.52162184692236	bayes_pls_golite062009
protein binding	0.405144403982597	bayes_pls_golite062009
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	0.152598505509111	bayes_pls_golite062009

Predicted Domain #4

Region A:
Residues: [408-467]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYLKPGTSYR LVHKSTGRNL HTHPVAAPVS KTQWEVSGYG DNVVGDNKDN WVIEIMDQRG  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	15.004365
Match:	PF02815.7
Description:	No description for PF02815.7 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [468-536]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEDPEKLHTL TTSFRIKNLE MGCYLAQTGN SLPEWGFRQQ EVVCMKNPFK RDKRTWWNIE  60
   61 THENERLPP

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	17.920819
Match:	PF02815.7
Description:	No description for PF02815.7 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6

Region A:
Residues: [537-759]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPEDFQYPKT NFLKDFIHLN LAMMATNNAL VPDPDKFDYL ASSAWQWPTL NVGLRLCGWG  60
   61 DDNPKYFLLG TPASTWASSV AVLAFMATVV ILLIRWQRQY VDLRNPSNWN VFLMGGFYPL 120
  121 LAWGLHYMPF VIMSRVTYVH HYLPALYFAL IILAYCFDAG LQKWSRSKCG RIMRFVLYAG 180
  181 FMALVIGCFW YFSPISFGME GPSSNFRYLN WFSTWDIADK QEA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: