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View Structure Prediction Details

Protein: SYN8
Organism: Saccharomyces cerevisiae
Length: 255 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SYN8.

Description E-value Query
Range
Subject
Range
gi|531458, gi|74... - gi|7447071|pir||G01485 syntaxin - human, gi|531458|gb|AAA20940.1| syntaxin [Homo sapiens]
1.0E-41 [3..253] [8..251]
gi|220902, gi|207127 - gi|220902|dbj|BAA02089.1| synaptotagmin associated 35kDa protein [Rattus norvegicus], gi|207127|gb|A...
gi|251470 - gi|251470|gb|AAB22525.1| syntaxin, P35A [rats, brain, Peptide Partial, 285 aa]
3.0E-39 [3..253] [34..277]
STX1A_BOVIN - Syntaxin-1A OS=Bos taurus GN=STX1A PE=1 SV=1
4.0E-39 [3..253] [37..280]
gi|28502901 - gi|28502901|gb|AAH47133.1| Stx1a protein [Mus musculus]
5.0E-39 [3..253] [36..279]
gi|7595847, gi|7... - gi|7595847|gb|AAF64478.1| syntaxin 1A [Macaca mulatta], gi|74136291|ref|NP_001028037.1| syntaxin 1B ...
5.0E-39 [3..253] [37..280]

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Predicted Domain #1
Region A:
Residues: [1-255]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVLKLGYEL DQLSDLVEER TRLVSVLKLA PTSNDNVTLK RQLGSILELL QKCAPNDELI  60
   61 SRYNTILDKI PDTAVDKELY RFQQQVARNT DEVSKESLKK VRFKNDDELT VMYKDDDEQD 120
  121 EESPLPSTHT PYKDEPLQSQ LQSQSQPQPP QPMVSNQELF INQQQQLLEQ DSHLGALSQS 180
  181 IGRTHDISLD LNNEIVSQND SLLVDLENLI DNNGRNLNRA SRSMHGFNNS RFKDNGNCVI 240
  241 ILVLIVVLLL LLLVL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.09691
Match: 1dn1B_
Description: Syntaxin 1A N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
SNAP receptor activity 2.83778981988519 bayes_pls_golite062009
protein binding 2.01524199895183 bayes_pls_golite062009
binding 1.63807440800487 bayes_pls_golite062009
transporter activity 0.487715383686856 bayes_pls_golite062009
SNARE binding 0.44377480710212 bayes_pls_golite062009
protein transporter activity 0.268987748407298 bayes_pls_golite062009
substrate-specific transporter activity 0.0443963926233321 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle