YRC Public Data Repository - Protein Structure Prediction

Protein:	VPS66
Organism:	Saccharomyces cerevisiae
Length:	300 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS66.

Description	E-value	Query Range	Subject Range
VPS66 - Cytoplasmic protein of unknown function involved in vacuolar protein sorting. LOA1_YEAST - Lysophosphatidic acid:oleoyl-CoA acyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 /... gi\|151942912 - gi\|151942912\|gb\|EDN61258.1\| vacuolar sorting protein [Saccharomyces cerevisiae YJM789] gi\|190408063 - gi\|190408063\|gb\|EDV11328.1\| vacuolar protein sorting protein 66 [Saccharomyces cerevisiae RM11-1a] gi\|207340267 - gi\|207340267\|gb\|EDZ68672.1\| YPR139Cp-like protein [Saccharomyces cerevisiae AWRI1631]	2.0E-86	[1..300]	[1..300]
gi\|85090151 - gi\|85090151\|ref\|XP_958281.1\| hypothetical protein NCU04580 [Neurospora crassa OR74A] gi\|32406646, gi\|... - gi\|32406646\|ref\|XP_323936.1\| predicted protein [Neurospora crassa], gi\|28950020\|emb\|CAD70775.1\| cons...	6.0E-59	[1..296]	[1..331]
gi\|23509675, gi\|... - gi\|23509675\|ref\|NP_702342.1\| hypothetical protein PF14_0453 [Plasmodium falciparum 3D7], gi\|23497524...	1.0E-54	[1..297]	[1..339]
gi\|82704478 - gi\|82704478\|ref\|XP_726572.1\| hypothetical protein [Plasmodium yoelii yoelii str. 17XNL] gi\|23482034 - gi\|23482034\|gb\|EAA18137.1\| hypothetical protein [Plasmodium yoelii yoelii]	2.0E-47	[36..298]	[3..285]
GPAT4_MOUSE - Glycerol-3-phosphate acyltransferase 4 OS=Mus musculus GN=Gpat4 PE=1 SV=1	4.0E-44	[26..210]	[158..363]
AGPAT9 - 1-acylglycerol-3-phosphate O-acyltransferase 9	7.0E-41	[26..210]	[139..344]
gi\|26452748, gi\|... - gi\|29824119\|gb\|AAP04020.1\| unknown protein [Arabidopsis thaliana], gi\|26452748\|dbj\|BAC43455.1\| unkno...	9.0E-40	[19..233]	[72..307]

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Predicted Domain #1

Region A:
Residues: [1-205]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKYTNWRDN GTGIAPFLPN TIRKPSKVMT ACLLGILGVK TIIMLPLIML YLLTGQNNLL  60
   61 GLILKFTFSW KEEITVQGIK KRDVRKSKHY PQKGKLYICN CTSPLDAFSV VLLAQGPVTL 120
  121 LVPSNDIVYK VSIREFINFI LAGGLDIKLY GHEVAELSQL GNTVNFMFAE GTSCNGKSVL 180
  181 PFSITGKKLK EFIDPSITTM NPAMA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [206-300]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTKKFELQTI QIKTNKTAIT TLPISNMEYL SRFLNKGINV KCKINEPQVL SDNLEELRVA  60
   61 LNGGDKYKLV SRKLDVESKR NFVKEYISDQ RKKRK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.872	0.113	protein targeting to vacuole	c.23.1	CheY-like

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits