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View Structure Prediction Details

Protein: MEP3
Organism: Saccharomyces cerevisiae
Length: 489 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MEP3.

Description E-value Query
Range
Subject
Range
MEP3 - Ammonium permease of high capacity and low affinity; belongs to a ubiquitous family of cytoplasmic m...
gi|151942911 - gi|151942911|gb|EDN61257.1| ammonium transporter [Saccharomyces cerevisiae YJM789]
MEP3_YEAST - Ammonium transporter MEP3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MEP3 PE=1 SV=1
gi|190408062 - gi|190408062|gb|EDV11327.1| NH4+ transporter [Saccharomyces cerevisiae RM11-1a]
gi|207340266 - gi|207340266|gb|EDZ68671.1| YPR138Cp-like protein [Saccharomyces cerevisiae AWRI1631]
0.0 [1..489] [1..489]
gi|67900952, gi|... - gi|67900952|ref|XP_680732.1| hypothetical protein AN7463.2 [Aspergillus nidulans FGSC A4], ref|XP_41...
gi|18693013 - gi|18693013|gb|AAL73117.1| ammonium transporter MEAA [Emericella nidulans]
0.0 [12..480] [45..515]
gi|85112788 - gi|85112788|ref|XP_964410.1| ammonium transporter MEP1 [Neurospora crassa OR74A]
gi|28926191, gi|... - gi|32420499|ref|XP_330693.1| hypothetical protein [Neurospora crassa], gi|28926191|gb|EAA35174.1| am...
0.0 [12..471] [30..489]
gi|17221150 - gi|17221150|gb|AAL11032.1| high affinity ammonium transporter [Tuber borchii]
0.0 [12..465] [33..483]
amt1 - ammonium transporter Amt1
AMT1_SCHPO - Ammonium transporter 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=amt1 PE=3 SV=1
0.0 [13..489] [28..492]
gi|15042695 - gi|15042695|gb|AAK82417.1| ammonium transporter [Hebeloma cylindrosporum]
0.0 [6..472] [2..467]
gi|15808693 - gi|15808693|gb|AAL08424.1|AF187870_1 probable ammonium transporter MEP1 [Ustilago maydis]
0.0 [13..470] [42..502]

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Predicted Domain #1
Region A:
Residues: [1-489]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARGDGHLWT ETYDSSTVAF MILGAALVFF MVPGLGFLYS GLARRKSALA LIWVVIMATL  60
   61 VGILQWYFWG YSLAFSKTAT NNKFIGNLDS FGFRNVYGKI SDDSTYPELI YAIFQMMFMC 120
  121 VALSIIAGAT AERGKLFPHM VFLFVFATLV YCPITYWIWA PGGWAYQWGV LDWAGGGNIE 180
  181 ILSAVAGFVY SYFLGRRKEN LLINFRPHNV SMVTLGTSIL WFGWLLFNAA SSLSPNMRSV 240
  241 YAFMNTCLSA TTGGMTWCLL DYRSEKKWST VGLCSGIICG LVAATPSSGC ITLYGSLIQG 300
  301 IIAGVVCNFA TKIKYYLKVD DSLDLLAEHG IAGVVGLIFN ALFAADWVIG MDGTTKHKGG 360
  361 WLTHNWKQMY IQIAYIGASA GYCAVVTAII CFVLGKIPGV HLRVTEEAEA LGLDEDQIGE 420
  421 FAYDYVEVRR DYYQWGVDTD ALHTTCNGAN SASETNPTED SQNSSLSSAT VSGQNEKSNN 480
  481 PKLHHAKEA

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 175.69897
Match: PF00909
Description: Ammonium Transporter Family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
ammonium transmembrane transporter activity 10.0624820335928 bayes_pls_golite062009
organic cation transmembrane transporter activity 9.07420898067257 bayes_pls_golite062009
cation transmembrane transporter activity 7.57181833547312 bayes_pls_golite062009
ion transmembrane transporter activity 7.46308808953548 bayes_pls_golite062009
methylammonium transmembrane transporter activity 7.38326654060024 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 7.08971867997216 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 7.03159982829686 bayes_pls_golite062009
transporter activity 5.3870893301235 bayes_pls_golite062009
transmembrane transporter activity 5.3046132351753 bayes_pls_golite062009
substrate-specific transporter activity 5.16067985999244 bayes_pls_golite062009
high affinity secondary active ammonium transmembrane transporter activity 3.56825523857899 bayes_pls_golite062009
amine transmembrane transporter activity 2.81164277777293 bayes_pls_golite062009
active transmembrane transporter activity 1.08017669832334 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle