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View Structure Prediction Details

Protein: KAR9
Organism: Saccharomyces cerevisiae
Length: 644 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KAR9.

Description E-value Query
Range
Subject
Range
gi|207340783 - gi|207340783|gb|EDZ69025.1| YPL269Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190407697 - gi|190407697|gb|EDV10962.1| karyogamy protein KAR9 [Saccharomyces cerevisiae RM11-1a]
KAR9_YEAST - Karyogamy protein KAR9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KAR9 PE=1 SV=2
KAR9 - Karyogamy protein required for correct positioning of the mitotic spindle and for orienting cytoplas...
0.0 [1..644] [1..644]

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Predicted Domain #1
Region A:
Residues: [1-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNDGPRSMT IGDDFQENFC ERLERIHNTL HSINDCNSLN ESTTSISETL LVQFYDDLEN  60
   61 VASVIPDLVN KKRLGKDDIL LFMDWLLLKK YMLYQFISDV HNIEEGFAHL LDLLEDEFSK 120
  121 DDQDSDKYNR FSPMFDVIEE STQIKTQLEP WLTNLKELLD TSLEFNEISK DHMDTLHKII 180
  181 NSNISYCLEI QEERFASPIR HTPSFTLEQL VKLLGTHTET TEPKVPKFSP AEDILSRKFL 240
  241 NLKKNIPPIE KSLTDILPQR IVQFGHRNIT NITTLQTILQ KKYELIMKDY RFMNSEFREL 300
  301 KVELIDKRWN ILFINLNHEL LYILDEIERL QSKLLTTKYT K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 5.50691080671938 bayes_pls_golite062009
actin binding 5.20020808032372 bayes_pls_golite062009
actin filament binding 4.56724410384698 bayes_pls_golite062009
tubulin binding 3.64804975825589 bayes_pls_golite062009
microtubule binding 3.62999428181677 bayes_pls_golite062009
binding 2.3468119246528 bayes_pls_golite062009
protein binding 2.03402581943916 bayes_pls_golite062009
structural constituent of cytoskeleton 1.75895219767628 bayes_pls_golite062009
integrin binding 0.634559226589946 bayes_pls_golite062009
structural constituent of muscle 0.502792536769221 bayes_pls_golite062009
SNARE binding 0.309596137075689 bayes_pls_golite062009
protein complex binding 0.180823251423251 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [342-644]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DITIRLERQL ERKSKTVSKT FNIIYRALEF SLLDAGVASK TNELAQRWLN IKPTADKILI  60
   61 KSSASNKIAT SKKKIPKPKS LGFGRPNSVI GTITQDFQER VAINEGDSNK TPENSTTVAL 120
  121 KGKKLGKALL QKMNIKPATS PNSSNAINPF FDPESPNKGK LILSSVPPLP YDETDETTLR 180
  181 VSRGENEKSP DSFITSRHEN KVQITETPLM AKNKSVLDIE KDKWNHYRSL PSRIPIYKDK 240
  241 VVKVTVENTP IAKVFQTPPT KITTPNSQVW VPSTRRRTRL RPPTPLSQLL SPREGRLDKT 300
  301 PTY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle