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View Structure Prediction Details

Protein: USV1
Organism: Saccharomyces cerevisiae
Length: 391 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for USV1.

Description E-value Query
Range
Subject
Range
ZNF347 - zinc finger protein 347
gi|208968133 - gi|208968133|dbj|BAG73905.1| zinc finger protein 347 [synthetic construct]
0.0 [1..391] [276..725]
gi|15929737, gi|... - gi|21703954|ref|NP_663458.1| zinc finger protein 160 [Mus musculus], gi|15929737|gb|AAH15291.1| Zinc...
0.0 [1..391] [189..610]

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Predicted Domain #1
Region A:
Residues: [1-115]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENTTNRNTA GVLTSSNGNF ATNSVAASTP KRSKSARRKT FKCTGYDGCT MSFTRAEHLA  60
   61 RHIRKHTGEK PFQCPACLKF FSRVDNLKQH RESVHAHKNH HSTSSHQRKP SSSSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 90.85005
Match: 1a1iA_
Description: ZIF268
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.70988788192472 bayes_pls_golite062009
nucleic acid binding 4.58713908116892 bayes_pls_golite062009
DNA binding 4.56219307357342 bayes_pls_golite062009
transcription activator activity 3.52873291636993 bayes_pls_golite062009
transcription factor activity 3.50954949535763 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.22082323675675 bayes_pls_golite062009
binding 3.10743787485868 bayes_pls_golite062009
sequence-specific DNA binding 2.53101891154822 bayes_pls_golite062009
chromatin binding 2.18464662431232 bayes_pls_golite062009
protein binding 2.05530362750351 bayes_pls_golite062009
transcription repressor activity 1.64349785387632 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.63161912031789 bayes_pls_golite062009
transcription factor binding 1.39608963544799 bayes_pls_golite062009
structure-specific DNA binding 0.790771220986801 bayes_pls_golite062009
transcription cofactor activity 0.77874411480713 bayes_pls_golite062009
double-stranded DNA binding 0.53991278722671 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009
transcription corepressor activity 0.10558148421807 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [116-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSSSASSSS SASSSTSYSD PYRKTNINSG NMPMMAENEK APQIIHSSPE FITSTR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [172-247]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIPPISPRSI YNTQRQQQHQ QQQHQQAPYY FPSHPITDSY YQYPLPSNNN TINYLPSVDV  60
   61 QYPLNVSPSS TSHPAS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [248-308]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVIISSFPPR SMPSTSFKYK DSADFQARTT MNKYNIRPSN INVNTSNINN HLDSFSPPFS  60
   61 P

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [309-391]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STTVAEAKPI ILPQYQQAFS QPPNGNKNNN MSSSKNGGKG GENFKNTDDR NDNNNKKRSE  60
   61 TLSESDISVN TNKKRLSVDY ILT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 86.144602
Match: 2adr__
Description: ADR1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle