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View Structure Prediction Details

Protein: NEW1
Organism: Saccharomyces cerevisiae
Length: 1196 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NEW1.

Description E-value Query
Range
Subject
Range
NEW1 - ATP binding cassette protein that cosediments with polysomes and is required for biogenesis of the s...
NEW1_YEAST - [NU+] prion formation protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NEW1 PE=...
0.0 [1..1196] [1..1196]
gi|2707897 - gi|2707897|gb|AAC35391.1| elongation-like factor [Candida albicans]
0.0 [28..1196] [30..1191]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [126..1116] [1..985]
EF3_CANGA - Elongation factor 3 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-...
EF3_CANGA - Elongation factor 3 OS=Candida glabrata GN=TEF3 PE=3 SV=2
0.0 [134..1131] [4..995]
EF3_SCHPO - Elongation factor 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=tef3 PE=1 SV=1
tef3 - translation elongation factor eEF3
0.0 [126..1165] [1..1040]
gi|32416300, gi|... - gi|32416300|ref|XP_328628.1| hypothetical protein [Neurospora crassa], gi|28924044|gb|EAA33202.1| el...
gi|85107753 - gi|85107753|ref|XP_962438.1| elongation factor 3 [Neurospora crassa OR74A]
0.0 [128..1196] [2..1055]

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Predicted Domain #1
Region A:
Residues: [1-172]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPKKFKDLN SFLDDQPKDP NLVASPFGGY FKNPAADAGS NNASKKSSYQ QQRNWKQGGN  60
   61 YQQGGYQSYN SNYNNYNNYN NYNNYNNYNN YNKYNGQGYQ KSTYKQSAVT PNQSGTPTPS 120
  121 ASTTSLTSLN EKLSNLELTP ISQFLSKIPE CQSITDCKNQ IKLIIEEFGK EG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [173-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSTGEKIEEW KIVDVLSKFI KPKNPSLVRE SAMLIISNIA QFFSGKPPQE AYLLPFFNVA  60
   61 LDCISDKENT VKRAAQHAID SLLNCFPMEA LTCFVLPTIL DYLSSGAK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.965 0.004 ATPase activity, coupled to transmembrane movement of substances a.118.9 ENTH/VHS domain

Predicted Domain #3
Region A:
Residues: [281-427]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WQAKMAALSV VDRIREDSAN DLLELTFKDA VPVLTDVATD FKPELAKQGY KTLLDYVSIL  60
   61 DNLDLSPRYK LIVDTLQDPS KVPESVKSLS SVTFVAEVTE PSLSLLVPIL NRSLNLSSSS 120
  121 QEQLRQTVIV VENLTRLVNN RNEIESF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.09691
Match: 1ii8B_
Description: Crystal structure of the P. furiosus Rad50 ATPase domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [428-498]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPLLLPGIQK VVDTASLPEV RELAEKALNV LKEDDEADKE NKFSGRLTLE EGRDFLLDHL  60
   61 KDIKADDSCF V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.09691
Match: 1ii8B_
Description: Crystal structure of the P. furiosus Rad50 ATPase domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [499-564]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPYMNDETVI KYMSKILTVD SNVNDWKRLE DFLTAVFGGS DSQREFVKQD FIHNLRALFY  60
   61 QEKERA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [565-767]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEDEGIEIVN TDFSLAYGSR MLLNKTNLRL LKGHRYGLCG RNGAGKSTLM RAIANGQLDG  60
   61 FPDKDTLRTC FVEHKLQGEE GDLDLVSFIA LDEELQSTSR EEIAAALESV GFDEERRAQT 120
  121 VGSLSGGWKM KLELARAMLQ KADILLLDEP TNHLDVSNVK WLEEYLLEHT DITSLIVSHD 180
  181 SGFLDTVCTD IIHYENKKLA YYK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 118.045757
Match: 1oxsC_
Description: Glucose transport protein GlcV, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [768-1033]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNLAAFVEQK PEAKSYYTLT DSNAQMRFPP PGILTGVKSN TRAVAKMTDV TFSYPGAQKP  60
   61 SLSHVSCSLS LSSRVACLGP NGAGKSTLIK LLTGELVPNE GKVEKHPNLR IGYIAQHALQ 120
  121 HVNEHKEKTA NQYLQWRYQF GDDREVLLKE SRKISEDEKE MMTKEIDIDD GRGKRAIEAI 180
  181 VGRQKLKKSF QYEVKWKYWK PKYNSWVPKD VLVEHGFEKL VQKFDDHEAS REGLGYRELI 240
  241 PSVITKHFED VGLDSEIANH TPLGSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.679424
Match: 1jsqA_
Description: MsbA
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [1034-1196]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGGQLVKVVI AGAMWNNPHL LVLDEPTNYL DRDSLGALAV AIRDWSGGVV MISHNNEFVG  60
   61 ALCPEQWIVE NGKMVQKGSA QVDQSKFEDG GNADAVGLKA SNLAKPSVDD DDSPANIKVK 120
  121 QRKKRLTRNE KKLQAERRRL RYIEWLSSPK GTPKPVDTDD EED

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle