YRC Public Data Repository - Protein Structure Prediction

Protein:	DAP1
Organism:	Saccharomyces cerevisiae
Length:	152 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DAP1.

Description	E-value	Query Range	Subject Range
DAP1_YEAST - Damage response protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DAP1 PE=1 SV=1 gi\|190407791 - gi\|190407791\|gb\|EDV11056.1\| damage response protein 1 [Saccharomyces cerevisiae RM11-1a] DAP1 - Heme-binding protein involved in regulation of cytochrome P450 protein Erg11p; damage response prote... gi\|151942629 - gi\|151942629\|gb\|EDN60975.1\| damage resistance protein [Saccharomyces cerevisiae YJM789]	6.0E-35	[1..152]	[1..152]
gi\|7689365 - gi\|7689365\|gb\|AAF67749.1\|AF254804_1 membrane steroid binding protein [Bos taurus]	3.0E-30	[1..147]	[26..163]
gi\|7513461 - pir\|\|JC5260 progesterone membrane binding protein - pig PGRC1_PIG - Membrane-associated progesterone receptor component 1 OS=Sus scrofa GN=PGRMC1 PE=1 SV=3	4.0E-30	[1..147]	[35..172]
PGRC1_MOUSE - Membrane-associated progesterone receptor component 1 OS=Mus musculus GN=Pgrmc1 PE=1 SV=4	1.0E-29	[1..147]	[35..173]
PGRMC1 - progesterone receptor membrane component 1 HGNC:16090\|MIM:3... - receptor membrane component 1 gi\|123981742, gi... - gi\|123996565\|gb\|ABM85884.1\| progesterone receptor membrane component 1 [synthetic construct], gi\|123...	1.0E-29	[1..147]	[35..173]
gi\|185134138, gi... - gi\|25046107\|gb\|AAL49963.1\| progestin membrane receptor component 1 [Oncorhynchus mykiss], gi\|1851341...	6.0E-28	[1..147]	[28..162]
gi\|220953468, gi... - gi\|220953468\|gb\|ACL89277.1\| CG9066-PA [synthetic construct], gi\|220943238\|gb\|ACL84162.1\| CG9066-PA [... MSBP-PB, MSBP-PA... - The gene membrane steroid binding protein is referred to in FlyBase by the symbol Dmel\MSBP (CG9066,...	7.0E-28	[1..147]	[46..183]
NIA2_ARATH - Nitrate reductase [NADH] 2 OS=Arabidopsis thaliana GN=NIA2 PE=1 SV=1	3.0E-27	[10..119]	[510..616]

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Predicted Domain #1

Region A:
Residues: [1-152]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFIKNLLFG GVKTSEDPTG LTGNGASNTN DSNKGSEPVV AGNFFPRTLS KFNGHDDEKI  60
   61 FIAIRGKVYD CTRGRQFYGP SGPYTNFAGH DASRGLALNS FDLDVIKDWD QPIDPLDDLT 120
  121 KEQIDALDEW QEHFENKYPC IGTLIPEPGV NV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.0
Match:	1eueA_
Description:	Cytochrome b5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.33785434389105	bayes_pls_golite062009
protein binding	0.368622185753917	bayes_pls_golite062009
steroid binding	0.177535173083536	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: